Summary of Study ST001185
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000796. The data can be accessed directly via it's Project DOI: 10.21228/M8SM3C This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001185 |
Study Title | Genetic and metabolic characterization of bioengineered human fatty liver tissue with modified SIRT1 expression |
Study Summary | Lipidomics and metabolomics was performed three types of tissue samples to compare human normal liver tissue against human NASH liver and the bioengineered human iPS-derived fatty liver tissue-iKD-SIRT1. The purpose of this study was to show that the global lipidomics profile of iPS-derived fatty liver tissue-iKD-SIRT1 was similar to that of patients with NASH |
Institute | University of Pittsburgh |
Department | Department of Pathology |
Last Name | Soto-Gutierrez |
First Name | Alejandro |
Address | 200 Lothrop Street, 423 Biomedical Science Tower, Pittsburgh, PA 15261, USA |
als208@pitt.edu | |
Phone | +14126480064 |
Submit Date | 2019-05-20 |
Num Groups | 3 |
Raw Data Available | Yes |
Analysis Type Detail | LC-MS |
Release Date | 2020-01-06 |
Release Version | 1 |
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Treatment:
Treatment ID: | TR001266 |
Treatment Summary: | Normal liver tissue and NASH liver tissue samples were not treated, and were directly analyzed for lipidomics profile. Bioengineered human iPS-derive fatty liver tissue was synthesized as described in the study referenced herein |