Summary of Study ST001825

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001153. The data can be accessed directly via it's Project DOI: 10.21228/M8P10F This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001825
Study TitleMetabolomic and lipidomic profiles of CKD in obese patients in serum and urine (part 2 of 3)
Study TypeHuman nephropathy in CKD obese patients
Study SummaryObesity is a global pandemic with an increase prevalence over the years. This condition elevates the risk of developing cardiovascular diseases, hypertension and renal pathologies, like chronic kidney disease (CKD). In the present study, the metabolomic and the lipidomic profiles of CKD obese patients were analyzed comparing with obese subjects without CKD. Subsequently, CKD obese patients underwent bariatric surgery and the effect of surgery in the CKD progression of these subjects was evaluated. Serum and urine were measured by LC-MS and GC-HRAM equipment.
Institute
University Rey Juan Carlos
DepartmentBasics Science of Health
Last NameLanzon
First NameBorja
AddressAvenida de Atenas S/N, Alcorcón, Madrid, 28922, Spain
Emailborja.lanzon@urjc.es
Phone663692554
Submit Date2021-04-02
Num Groups3
Total Subjects35
Study CommentsSerum GC-HRAM data: part 2 of 3.
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailGC-MS
Release Date2021-06-14
Release Version1
Borja Lanzon Borja Lanzon
https://dx.doi.org/10.21228/M8P10F
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR001915
Treatment Summary:30 µl of serum of each sample were randomized and vortex-mixed with 400 µl of MeOH at -20 °C containing 1 ppm of a mix of internal standards. Samples were oximated and silylated. Samples were analyzed in a Orbitrap system.
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