Summary of Study ST002985
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001831. The data can be accessed directly via it's Project DOI: 10.21228/M81Q73 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002985 |
Study Title | Polar metabolomics of in vitro digestions of commercial cow's milk formula. |
Study Type | (un)targeted MS |
Study Summary | This study is part of a multi-part study, including a. longitudinal polar fecal metabolomics of mice undergoing sensitization to beta-lactoglobulin b. polar fecal metabolomics of a patient cohort c. fecal lipidomics of a patient cohort d. polar urinary metabolomics of a patient cohort e. polar metabolomics of in vitro digestions. This specific part is part e. polar metabolomics of in vitro digestions |
Institute | Ghent University |
Department | Department of Translational Physiology, Infectiology and Public Health |
Laboratory | Laboratory for Integrative Metabolomics |
Last Name | De Paepe |
First Name | Ellen |
Address | Salisburylaan 133, 9820 Merelbeke, Belgium |
Ellen.DePaepe@UGent.be | |
Phone | 0032479081098 |
Submit Date | 2023-07-05 |
Num Groups | 4 |
Total Subjects | 81 |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Thermo) |
Analysis Type Detail | LC-MS |
Release Date | 2023-11-29 |
Release Version | 1 |
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Treatment:
Treatment ID: | TR003107 |
Treatment Summary: | Two different CMP powder formulations were used, i.e., Nutrilon 1 and Nutrilon Pepti 1 (Nutricia, Amsterdam, The Netherlands). Feces were obtained from 6 children within the original cohort (<2 years old; 50% girls), without a history of antibiotic treatment 6 months prior to donation. Among the 6 participants, 2 children suffered from IgE-CMA, and 2 were designated as healthy controls. In vitro simulation of the gastrointestinal digestion consisted of enzymatic digestion (mouth, stomach, and duodenum) followed by colonic fermentation. |
Treatment Compound: | Nutrilon 1 and Nutrilon Pepti 1 |
Treatment Dose: | 920 mg |
Treatment Doseduration: | 1 |