MGP Database

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MGP000007

Ontology/Pathway Information

Entrez Gene ID19
Gene NameATP-binding cassette, sub-family A (ABC1), member 1
Gene Symbol ABCA1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030139 IDA:BHF-UCLCendocytic vesicle
GO:0009897 IEA:EnsemblCexternal side of plasma membrane
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0034364 IEA:EnsemblChigh-density lipoprotein particle
GO:0005887 IDA:BHF-UCLCintegral component of plasma membrane
GO:0045121 IDA:BHF-UCLCmembrane raft
GO:0048471 IDA:BHF-UCLCperinuclear region of cytoplasm
GO:0045335 IDA:BHF-UCLCphagocytic vesicle
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0008509 ISS:BHF-UCLFanion transmembrane transporter activity
GO:0034186 IPI:BHF-UCLFapolipoprotein A-I binding
GO:0034188 IDA:BHF-UCLFapolipoprotein A-I receptor activity
GO:0034185 IPI:BHF-UCLFapolipoprotein binding
GO:0016887 IEA:InterProFATPase activity
GO:0051117 IPI:BHF-UCLFATPase binding
GO:0005524 IDA:BHF-UCLFATP binding
GO:0015485 IC:BHF-UCLFcholesterol binding
GO:0017127 IDA:BHF-UCLFcholesterol transporter activity
GO:0005543 IC:BHF-UCLFphospholipid binding
GO:0005548 IDA:BHF-UCLFphospholipid transporter activity
GO:0005102 IPI:BHF-UCLFreceptor binding
GO:0031267 IPI:BHF-UCLFsmall GTPase binding
GO:0019905 IPI:BHF-UCLFsyntaxin binding
GO:0038027 IDA:GOCPapolipoprotein A-I-mediated signaling pathway
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0071397 IEA:EnsemblPcellular response to cholesterol
GO:0071222 IEA:EnsemblPcellular response to lipopolysaccharide
GO:0071300 IEA:EnsemblPcellular response to retinoic acid
GO:0033344 IDA:BHF-UCLPcholesterol efflux
GO:0042632 IDA:BHF-UCLPcholesterol homeostasis
GO:0008203 IDA:BHF-UCLPcholesterol metabolic process
GO:0016197 IDA:BHF-UCLPendosomal transport
GO:0007186 IMP:BHF-UCLPG-protein coupled receptor signaling pathway
GO:0034380 IMP:BHF-UCLPhigh-density lipoprotein particle assembly
GO:0050702 IMP:BHF-UCLPinterleukin-1 beta secretion
GO:0032367 IMP:BHF-UCLPintracellular cholesterol transport
GO:0042157 TAS:ReactomePlipoprotein metabolic process
GO:0007040 IDA:BHF-UCLPlysosome organization
GO:0010887 TAS:BHF-UCLPnegative regulation of cholesterol storage
GO:0010745 TAS:BHF-UCLPnegative regulation of macrophage derived foam cell differentiation
GO:0002790 IEA:EnsemblPpeptide secretion
GO:0006911 IEA:EnsemblPphagocytosis, engulfment
GO:0033700 IDA:BHF-UCLPphospholipid efflux
GO:0055091 IMP:BHF-UCLPphospholipid homeostasis
GO:0045332 IEA:EnsemblPphospholipid translocation
GO:0060155 IMP:BHF-UCLPplatelet dense granule organization
GO:0030819 IMP:BHF-UCLPpositive regulation of cAMP biosynthetic process
GO:0010875 IEA:EnsemblPpositive regulation of cholesterol efflux
GO:0006497 IEA:EnsemblPprotein lipidation
GO:0032489 IMP:BHF-UCLPregulation of Cdc42 protein signal transduction
GO:0042493 IEA:EnsemblPresponse to drug
GO:0034616 IEP:BHF-UCLPresponse to laminar fluid shear stress
GO:0055098 IEP:BHF-UCLPresponse to low-density lipoprotein particle
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0043691 IMP:BHF-UCLPreverse cholesterol transport
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_13621HDL-mediated lipid transport
REACT_602Lipid digestion, mobilization, and transport
REACT_6823Lipoprotein metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_116145PPARA activates gene expression
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
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