MGP Database

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MGP000017

Ontology/Pathway Information

Entrez Gene ID32
Gene Nameacetyl-CoA carboxylase beta
Gene Symbol ACACB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0012505 IEA:UniProtKB-SubCellCendomembrane system
GO:0005741 TAS:ReactomeCmitochondrial outer membrane
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0005634 IDA:UniProtKBCnucleus
GO:0003989 IDA:UniProtKBFacetyl-CoA carboxylase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0009374 IEA:EnsemblFbiotin binding
GO:0004075 IEA:UniProtKB-ECFbiotin carboxylase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0006084 IDA:UniProtKBPacetyl-CoA metabolic process
GO:0006768 TAS:ReactomePbiotin metabolic process
GO:0006853 TAS:ReactomePcarnitine shuttle
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0006633 IEA:UniProtKB-KWPfatty acid biosynthetic process
GO:2001295 IEA:UniProtKB-UniPathwayPmalonyl-CoA biosynthetic process
GO:0031325 TAS:ReactomePpositive regulation of cellular metabolic process
GO:0051289 IDA:UniProtKBPprotein homotetramerization
GO:0042493 IEA:EnsemblPresponse to drug
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147904Activation of gene expression by SREBF (SREBP)
REACT_11153Biotin transport and metabolism
REACT_2122ChREBP activates metabolic gene expression
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_11082Import of palmitoyl-CoA into the mitochondrial matrix
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_147797Regulation of cholesterol biosynthesis by SREBP (SREBF)
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