MGP Database

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MGP000019

Ontology/Pathway Information

Entrez Gene ID34
Gene Nameacyl-CoA dehydrogenase, C-4 to C-12 straight chain
Gene Symbol ACADM
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 IDA:UniProtKBCaxon
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:LIFEdbCmitochondrion
GO:0005634 IDA:UniProtKBCnucleus
GO:0003995 IMP:UniProtKBFacyl-CoA dehydrogenase activity
GO:0050660 IEA:InterProFflavin adenine dinucleotide binding
GO:0042802 IDA:BHF-UCLFidentical protein binding
GO:0070991 IDA:BHF-UCLFmedium-chain-acyl-CoA dehydrogenase activity
GO:0045329 IMP:BHF-UCLPcarnitine biosynthetic process
GO:0019254 IMP:BHF-UCLPcarnitine metabolic process, CoA-linked
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0006635 IMP:UniProtKBPfatty acid beta-oxidation
GO:0033539 IDA:BHF-UCLPfatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0051793 IDA:BHF-UCLPmedium-chain fatty acid catabolic process
GO:0051791 IDA:BHF-UCLPmedium-chain fatty acid metabolic process
GO:0055114 IDA:BHF-UCLPoxidation-reduction process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1708Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
REACT_1697Beta oxidation of octanoyl-CoA to hexanoyl-CoA
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_1473Mitochondrial Fatty Acid Beta-Oxidation
REACT_1541mitochondrial fatty acid beta-oxidation of saturated fatty acids
REACT_160mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
REACT_116145PPARA activates gene expression
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
SMP Pathway Links
SMP IDDescription
SMP001372-Methyl-3-Hydroxybutryl CoA Dehydrogenase Deficiency
SMP001383-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency
SMP005213-hydroxyisobutyric acid dehydrogenase deficiency
SMP005223-hydroxyisobutyric aciduria
SMP002373-Methylcrotonyl Coa Carboxylase Deficiency Type I
SMP001393-Methylglutaconic Aciduria Type I
SMP001403-Methylglutaconic Aciduria Type III
SMP001413-Methylglutaconic Aciduria Type IV
SMP00173Beta-Ketothiolase Deficiency
SMP00538Carnitine palmitoyl transferase deficiency (I)
SMP00541Carnitine palmitoyl transferase deficiency (II)
SMP00181Ethylmalonic Encephalopathy
SMP00051Fatty acid Metabolism
SMP00185Glutaric Aciduria Type I
SMP00523Isobutyryl-coa dehydrogenase deficiency
SMP00524Isovaleric acidemia
SMP00238Isovaleric Aciduria
SMP00539Long chain acyl-CoA dehydrogenase deficiency (LCAD)
SMP00198Malonic Aciduria
SMP00502Malonyl-coa decarboxylase deficiency
SMP00199Maple Syrup Urine Disease
SMP00542Medium chain acyl-coa dehydrogenase deficiency (MCAD)
SMP00384Methylmalonate Semialdehyde Dehydrogenase Deficiency
SMP00200Methylmalonic Aciduria
SMP00201Methylmalonic Aciduria Due to Cobalamin-Related Disorders
SMP00481Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids
SMP00016Propanoate Metabolism
SMP00236Propionic Acidemia
SMP00235Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)
SMP00545Trifunctional protein deficiency
SMP00032Valine, Leucine and Isoleucine Degradation
SMP00540Very-long-chain acyl coa dehydrogenase deficiency (VLCAD)
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