MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000022

Ontology/Pathway Information

Entrez Gene ID37
Gene Nameacyl-CoA dehydrogenase, very long chain
Gene Symbol ACADVL
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005743 IEA:UniProtKB-SubCellCmitochondrial inner membrane
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0042645 IDA:BHF-UCLCmitochondrial nucleoid
GO:0005739 ISS:BHF-UCLCmitochondrion
GO:0005730 IDA:HPACnucleolus
GO:0005634 IDA:HPACnucleus
GO:0003995 TAS:ReactomeFacyl-CoA dehydrogenase activity
GO:0050660 IEA:InterProFflavin adenine dinucleotide binding
GO:0004466 TAS:ProtIncFlong-chain-acyl-CoA dehydrogenase activity
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0015980 TAS:ProtIncPenergy derivation by oxidation of organic compounds
GO:0030855 IEP:UniProtKBPepithelial cell differentiation
GO:0006635 TAS:ReactomePfatty acid beta-oxidation
GO:0033539 ISS:BHF-UCLPfatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0045717 ISS:BHF-UCLPnegative regulation of fatty acid biosynthetic process
GO:0046322 ISS:BHF-UCLPnegative regulation of fatty acid oxidation
GO:0090181 ISS:BHF-UCLPregulation of cholesterol metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0001659 ISS:BHF-UCLPtemperature homeostasis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_2025Beta oxidation of palmitoyl-CoA to myristoyl-CoA
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_18368IRE1alpha activates chaperones
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_17015Metabolism of proteins
REACT_1473Mitochondrial Fatty Acid Beta-Oxidation
REACT_1541mitochondrial fatty acid beta-oxidation of saturated fatty acids
REACT_18356Unfolded Protein Response (UPR)
REACT_18273XBP1(S) activates chaperone genes
SMP Pathway Links
SMP IDDescription
SMP00538Carnitine palmitoyl transferase deficiency (I)
SMP00541Carnitine palmitoyl transferase deficiency (II)
SMP00181Ethylmalonic Encephalopathy
SMP00051Fatty acid Metabolism
SMP00185Glutaric Aciduria Type I
SMP00539Long chain acyl-CoA dehydrogenase deficiency (LCAD)
SMP00542Medium chain acyl-coa dehydrogenase deficiency (MCAD)
SMP00235Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)
SMP00545Trifunctional protein deficiency
SMP00540Very-long-chain acyl coa dehydrogenase deficiency (VLCAD)
  logo