MGP Database

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MGP000023

Ontology/Pathway Information

Entrez Gene ID38
Gene Nameacetyl-CoA acetyltransferase 1
Gene Symbol ACAT1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005743 IEA:EnsemblCmitochondrial inner membrane
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:HPACmitochondrion
GO:0003985 EXP:ReactomeFacetyl-CoA C-acetyltransferase activity
GO:0050662 IEA:EnsemblFcoenzyme binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0060612 IEA:EnsemblPadipose tissue development
GO:0007420 IEA:EnsemblPbrain development
GO:0009083 TAS:ReactomePbranched-chain amino acid catabolic process
GO:0046950 TAS:ReactomePcellular ketone body metabolic process
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0046951 TAS:ReactomePketone body biosynthetic process
GO:0046952 TAS:ReactomePketone body catabolic process
GO:0001889 IEA:EnsemblPliver development
GO:0072229 IEA:EnsemblPmetanephric proximal convoluted tubule development
GO:0051260 IEA:EnsemblPprotein homooligomerization
GO:0009725 IEA:EnsemblPresponse to hormone
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
GO:0042594 IEA:EnsemblPresponse to starvation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_197Branched-chain amino acid catabolism
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_1861Ketone body metabolism
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_22258Metabolism of lipids and lipoproteins
REACT_1464Synthesis of Ketone Bodies
REACT_59Utilization of Ketone Bodies
SMP Pathway Links
SMP IDDescription
SMP007192-aminoadipic 2-oxoadipic aciduria
SMP001372-Methyl-3-Hydroxybutryl CoA Dehydrogenase Deficiency
SMP001383-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency
SMP005213-hydroxyisobutyric acid dehydrogenase deficiency
SMP005223-hydroxyisobutyric aciduria
SMP002373-Methylcrotonyl Coa Carboxylase Deficiency Type I
SMP001393-Methylglutaconic Aciduria Type I
SMP001403-Methylglutaconic Aciduria Type III
SMP001413-Methylglutaconic Aciduria Type IV
SMP00173Beta-Ketothiolase Deficiency
SMP00073Butyrate Metabolism
SMP00538Carnitine palmitoyl transferase deficiency (I)
SMP00541Carnitine palmitoyl transferase deficiency (II)
SMP00181Ethylmalonic Encephalopathy
SMP00051Fatty acid Metabolism
SMP00185Glutaric Aciduria Type I
SMP00186Glutaric Aciduria Type III
SMP00527Hyperlysinemia I, Familial
SMP00528Hyperlysinemia II or Saccharopinuria
SMP00523Isobutyryl-coa dehydrogenase deficiency
SMP00524Isovaleric acidemia
SMP00238Isovaleric Aciduria
SMP00071Ketone Body Metabolism
SMP00196Leigh Syndrome
SMP00539Long chain acyl-CoA dehydrogenase deficiency (LCAD)
SMP00037Lysine Degradation
SMP00198Malonic Aciduria
SMP00502Malonyl-coa decarboxylase deficiency
SMP00199Maple Syrup Urine Disease
SMP00542Medium chain acyl-coa dehydrogenase deficiency (MCAD)
SMP00384Methylmalonate Semialdehyde Dehydrogenase Deficiency
SMP00200Methylmalonic Aciduria
SMP00201Methylmalonic Aciduria Due to Cobalamin-Related Disorders
SMP00480Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
SMP00558Primary hyperoxaluria II, PH2
SMP00016Propanoate Metabolism
SMP00236Propionic Acidemia
SMP00571Pyridoxine dependency with seizures
SMP00334Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
SMP00212Pyruvate Dehydrogenase Complex Deficiency
SMP00559Pyruvate kinase deficiency
SMP00060Pyruvate Metabolism
SMP00239Saccharopinuria/Hyperlysinemia II
SMP00568Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (SCHAD)
SMP00235Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)
SMP00569Succinyl CoA: 3-ketoacid CoA transferase deficiency
SMP00545Trifunctional protein deficiency
SMP00032Valine, Leucine and Isoleucine Degradation
SMP00540Very-long-chain acyl coa dehydrogenase deficiency (VLCAD)
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