MGP Database

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MGP000042

Ontology/Pathway Information

Entrez Gene ID87
Gene Nameactinin, alpha 1
Gene Symbol ACTN1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0042995 IDA:UniProtKBCcell projection
GO:0030864 IEA:EnsemblCcortical actin cytoskeleton
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0043197 IEA:EnsemblCdendritic spine
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005916 IEA:EnsemblCfascia adherens
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005634 IEA:EnsemblCnucleus
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0031093 TAS:ReactomeCplatelet alpha granule lumen
GO:0031143 TAS:UniProtKBCpseudopodium
GO:0001726 IEA:UniProtKB-SubCellCruffle
GO:0001725 IEA:EnsemblCstress fiber
GO:0030018 IEA:UniProtKB-SubCellCZ disc
GO:0005509 IEA:InterProFcalcium ion binding
GO:0003725 IDA:MGIFdouble-stranded RNA binding
GO:0005178 IDA:UniProtKBFintegrin binding
GO:0044325 IPI:BHF-UCLFion channel binding
GO:0017166 IPI:UniProtKBFvinculin binding
GO:0051764 IEA:InterProPactin crosslink formation
GO:0051017 IEA:EnsemblPactin filament bundle assembly
GO:0007596 TAS:ReactomePblood coagulation
GO:0034329 TAS:ReactomePcell junction assembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0048041 IMP:UniProtKBPfocal adhesion assembly
GO:0051271 IMP:UniProtKBPnegative regulation of cellular component movement
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0042981 NAS:UniProtKBPregulation of apoptotic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111155Cell-Cell communication
REACT_20649Cell-extracellular matrix interactions
REACT_20676Cell junction organization
REACT_118779Extracellular matrix organization
REACT_604Hemostasis
REACT_23832Nephrin interactions
REACT_163874Non-integrin membrane-ECM interactions
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_20580Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_163942Syndecan interactions
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