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MGP000060

UniProt Annotations

Entry Information
Gene Nameadenylate cyclase 7
Protein EntryADCY7_HUMAN
UniProt IDP51828
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityATP = 3',5'-cyclic AMP + diphosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 2 magnesium ions per subunit. {ECO:0000250};
FunctionThis is a membrane-bound, calcium-inhibitable adenylyl cyclase.
Sequence CautionSequence=BAA05021.2; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the adenylyl cyclase class-4/guanylyl cyclase family. {ECO:0000255|PROSITE-ProRule:PRU00099}.
SimilarityContains 2 guanylate cyclase domains. {ECO:0000255|PROSITE-ProRule:PRU00099}.
Subcellular LocationMembrane; Multi-pass membrane protein.
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