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MGP000070

UniProt Annotations

Entry Information
Gene Namealcohol dehydrogenase 6 (class V)
Protein EntryADH6_HUMAN
UniProt IDP28332
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P28332-1; Sequence=Displayed; Name=2; IsoId=P28332-2; Sequence=VSP_037702;
Catalytic ActivityAn alcohol + NAD(+) = an aldehyde or ketone + NADH.
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
MiscellaneousThere are 7 different ADH's isozymes in human: three belongs to class-I: alpha, beta, and gamma, one to class-II: pi, one to class-III: chi, one to class-IV: ADH7 and one to class- V: ADH6.
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. {ECO:0000305}.
Subcellular LocationCytoplasm.
Tissue SpecificityStomach and liver.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/adh6/";
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