MGP Database

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MGP000076

Ontology/Pathway Information

Entrez Gene ID136
Gene Nameadenosine A2b receptor
Gene Symbol ADORA2B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0001609 IEA:InterProFG-protein coupled adenosine receptor activity
GO:0007190 TAS:ProtIncPactivation of adenylate cyclase activity
GO:0000187 TAS:ProtIncPactivation of MAPK activity
GO:0007189 IEA:EnsemblPadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0006968 TAS:ProtIncPcellular defense response
GO:0031668 IEA:EnsemblPcellular response to extracellular stimulus
GO:0007588 TAS:ProtIncPexcretion
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0007254 TAS:ProtIncPJNK cascade
GO:0032722 IEA:EnsemblPpositive regulation of chemokine production
GO:0002882 IEA:EnsemblPpositive regulation of chronic inflammatory response to non-antigenic stimulus
GO:0031284 IEA:EnsemblPpositive regulation of guanylate cyclase activity
GO:0032755 IEA:EnsemblPpositive regulation of interleukin-6 production
GO:0043306 IEA:EnsemblPpositive regulation of mast cell degranulation
GO:0010575 IEA:EnsemblPpositive regulation vascular endothelial growth factor production
GO:0060087 IEA:EnsemblPrelaxation of vascular smooth muscle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18288Adenosine P1 receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19327G alpha (s) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_18342Nucleotide-like (purinergic) receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00321Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
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