MGP Database

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MGP000099

Ontology/Pathway Information

Entrez Gene ID182
Gene Namejagged 1
Gene Symbol JAG1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0045177 IEA:EnsemblCapical part of cell
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005887 NAS:UniProtKBCintegral component of plasma membrane
GO:0016020 TAS:UniProtKBCmembrane
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0005509 IEA:InterProFcalcium ion binding
GO:0008083 NAS:UniProtKBFgrowth factor activity
GO:0005112 NAS:UniProtKBFNotch binding
GO:0005198 NAS:UniProtKBFstructural molecule activity
GO:0001525 NAS:UniProtKBPangiogenesis
GO:0035909 ISS:BHF-UCLPaorta morphogenesis
GO:0042491 IEA:EnsemblPauditory receptor cell differentiation
GO:0001974 IEA:EnsemblPblood vessel remodeling
GO:0061309 ISS:BHF-UCLPcardiac neural crest cell development involved in outflow tract morphogenesis
GO:0003215 ISS:BHF-UCLPcardiac right ventricle morphogenesis
GO:0060411 ISS:BHF-UCLPcardiac septum morphogenesis
GO:0001709 NAS:UniProtKBPcell fate determination
GO:0061073 IEA:EnsemblPciliary body morphogenesis
GO:0072017 IEA:EnsemblPdistal tubule development
GO:0061444 ISS:BHF-UCLPendocardial cushion cell development
GO:0045446 NAS:UniProtKBPendothelial cell differentiation
GO:0030097 NAS:UniProtKBPhemopoiesis
GO:0030216 NAS:UniProtKBPkeratinocyte differentiation
GO:0072070 IEA:EnsemblPloop of Henle development
GO:0002011 IEA:EnsemblPmorphogenesis of an epithelial sheet
GO:0045445 NAS:UniProtKBPmyoblast differentiation
GO:0045599 IEA:EnsemblPnegative regulation of fat cell differentiation
GO:0045665 IEA:EnsemblPnegative regulation of neuron differentiation
GO:2000737 IMP:UniProtKBPnegative regulation of stem cell differentiation
GO:0007399 NAS:UniProtKBPnervous system development
GO:0097150 IEP:UniProtKBPneuronal stem cell maintenance
GO:0007220 TAS:ReactomePNotch receptor processing
GO:0061314 IMP:BHF-UCLPNotch signaling involved in heart development
GO:0007219 IMP:UniProtKBPNotch signaling pathway
GO:0045639 IEA:EnsemblPpositive regulation of myeloid cell differentiation
GO:0045747 IEA:EnsemblPpositive regulation of Notch signaling pathway
GO:0045669 IEA:EnsemblPpositive regulation of osteoblast differentiation
GO:0045944 IMP:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0061156 IMP:BHF-UCLPpulmonary artery morphogenesis
GO:0003184 IMP:BHF-UCLPpulmonary valve morphogenesis
GO:0030334 NAS:UniProtKBPregulation of cell migration
GO:0042127 NAS:UniProtKBPregulation of cell proliferation
GO:0032495 IEA:EnsemblPresponse to muramyl dipeptide
GO:0002456 IMP:UniProtKBPT cell mediated immunity
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118614Activated NOTCH1 Transmits Signal to the Nucleus
REACT_160089Constitutive Signaling by NOTCH1 HD Domain Mutants
REACT_160254Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
REACT_160243Constitutive Signaling by NOTCH1 PEST Domain Mutants
REACT_160106Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
REACT_116125Disease
REACT_160099FBXW7 Mutants and NOTCH1 in Cancer
REACT_160205NOTCH2 Activation and Transmission of Signal to the Nucleus
REACT_299Signaling by NOTCH
REACT_118859Signaling by NOTCH1
REACT_160133Signaling by NOTCH1 HD Domain Mutants in Cancer
REACT_160248Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
REACT_160214Signaling by NOTCH1 in Cancer
REACT_160301Signaling by NOTCH1 PEST Domain Mutants in Cancer
REACT_160082Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
REACT_118721Signaling by NOTCH2
REACT_118862Signaling by NOTCH3
REACT_118636Signaling by NOTCH4
REACT_111102Signal Transduction
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