MGP Database

MGP000104

Ontology/Pathway Information

Entrez Gene ID	189
Gene Name	alanine-glyoxylate aminotransferase
Gene Symbol	AGXT
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005759	IEA:UniProtKB-SubCell	C	mitochondrial matrix
GO:0005782	IDA:UniProtKB	C	peroxisomal matrix
GO:0005777	IDA:UniProtKB	C	peroxisome
GO:0008453	IDA:UniProtKB	F	alanine-glyoxylate transaminase activity
GO:0016597	IDA:UniProtKB	F	amino acid binding
GO:0042803	IDA:UniProtKB	F	protein homodimerization activity
GO:0030170	IDA:UniProtKB	F	pyridoxal phosphate binding
GO:0005102	IPI:UniProtKB	F	receptor binding
GO:0004760	IEA:UniProtKB-EC	F	serine-pyruvate transaminase activity
GO:0008483	IDA:UniProtKB	F	transaminase activity
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0019265	IDA:UniProtKB	P	glycine biosynthetic process, by transamination of glyoxylate
GO:0009436	IDA:UniProtKB	P	glyoxylate catabolic process
GO:0046487	IMP:HGNC	P	glyoxylate metabolic process
GO:0042853	IDA:UniProtKB	P	L-alanine catabolic process
GO:0019448	IDA:UniProtKB	P	L-cysteine catabolic process
GO:0046724	IEA:Ensembl	P	oxalic acid secretion
GO:0042866	IEA:Ensembl	P	pyruvate biosynthetic process
GO:0051591	IEA:Ensembl	P	response to cAMP
GO:0051384	IEA:Ensembl	P	response to glucocorticoid
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_16925	Glyoxylate metabolism
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives

SMP Pathway Links

SMP ID	Description
SMP00721	3-Phosphoglycerate dehydrogenase deficiency
SMP00055	Alanine Metabolism
SMP00179	Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
SMP00242	Dimethylglycine Dehydrogenase Deficiency
SMP00484	Dimethylglycinuria
SMP00004	Glycine and Serine Metabolism
SMP00485	Hyperglycinemia, non-ketotic
SMP00313	Lactic Acidemia
SMP00223	Non Ketotic Hyperglycinemia
SMP00352	Primary Hyperoxaluria Type I
SMP00350	Pyruvate Carboxylase Deficiency
SMP00244	Sarcosinemia