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MGP Database

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MGP000112

Ontology/Pathway Information

Entrez Gene ID	212
Gene Name	5'-aminolevulinate synthase 2
Gene Symbol	ALAS2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005743	IDA:UniProtKB	C	mitochondrial inner membrane
GO:0005759	TAS:Reactome	C	mitochondrial matrix
GO:0005739	IDA:UniProtKB	C	mitochondrion
GO:0003870	IDA:UniProtKB	F	5-aminolevulinate synthase activity
GO:0050662	ISS:UniProtKB	F	coenzyme binding
GO:0016594	ISS:UniProtKB	F	glycine binding
GO:0030170	IEA:InterPro	F	pyridoxal phosphate binding
GO:0006879	ISS:UniProtKB	P	cellular iron ion homeostasis
GO:0030218	ISS:UniProtKB	P	erythrocyte differentiation
GO:0006783	ISS:UniProtKB	P	heme biosynthetic process
GO:0042541	ISS:UniProtKB	P	hemoglobin biosynthetic process
GO:0032364	NAS:UniProtKB	P	oxygen homeostasis
GO:0006778	TAS:Reactome	P	porphyrin-containing compound metabolic process
GO:0006782	IEA:UniProtKB-UniPathway	P	protoporphyrinogen IX biosynthetic process
GO:0001666	IDA:UniProtKB	P	response to hypoxia
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_9465	Heme biosynthesis
REACT_111217	Metabolism
REACT_9431	Metabolism of porphyrins