MGP Database

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MGP000120

Record overview

MGPD IDMGP000120
Gene ID220
SpeciesHomo sapiens (Human)
Gene Namealdehyde dehydrogenase 1 family, member A3
Gene Symbol ALDH1A3
SynonymsALDH6; MCOP8; RALDH3; ALDH1A6;
Alternate namesaldehyde dehydrogenase family 1 member A3; acetaldehyde dehydrogenase 6; aldehyde dehydrogenase 6; retinaldehyde dehydrogenase 3;
Chromosome15
Map Location15q26.3
EC Number1.2.1.5
SummaryThis gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
OrthologsView orthologs and multiple alignments for ALDH1A3

Proteins

aldehyde dehydrogenase family 1 member A3 isoform 1
Refseq ID:NP_000684
Protein GI:153266822
UniProt ID:P47895
mRNA ID:NM_000693
Length:512
RefSeq Status:
MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLL
HQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNT
MVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE
CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSE
VTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEV
KTVTIKLGDKNP
 
aldehyde dehydrogenase family 1 member A3 isoform 2
Refseq ID:NP_001280744
Protein GI:658310017
UniProt ID:P47895
mRNA ID:NM_001293815
Length:405
RefSeq Status:
MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLL
HQLADLVERDRATLAAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVF
FNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRI
AKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL
GDKNP
 
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