MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000123

UniProt Annotations

Entry Information
Gene NameATP-binding cassette, sub-family D (ALD), member 2
Protein EntryABCD2_HUMAN
UniProt IDQ9UBJ2
SpeciesHuman
Comments
Comment typeDescription
FunctionProbable transporter.
SimilarityBelongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily. {ECO:0000305}.
SimilarityContains 1 ABC transmembrane type-1 domain. {ECO:0000255|PROSITE-ProRule:PRU00441}.
SimilarityContains 1 ABC transporter domain. {ECO:0000255|PROSITE-ProRule:PRU00434}.
Subcellular LocationPeroxisome membrane; Multi-pass membrane protein.
SubunitCan form heterodimers with ABCD1/ALD and ABCD3/PMP70. Dimerization is necessary to form an active transporter. Interacts with PEX19. {ECO:0000269|PubMed:10551832, ECO:0000269|PubMed:10704444, ECO:0000269|PubMed:10777694}.
Tissue SpecificityPredominantly expressed in brain and heart.
Web ResourceName=ABCMdb; Note=Database for mutations in ABC proteins; URL="http://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q9UBJ2";
  logo