MGP Database

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MGP000131

Ontology/Pathway Information

Entrez Gene ID242
Gene Namearachidonate 12-lipoxygenase, 12R type
Gene Symbol ALOX12B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0004052 IMP:UniProtKBFarachidonate 12-lipoxygenase activity
GO:0005506 IEA:InterProFiron ion binding
GO:1990136 ISS:UniProtKBFlinoleate 9S-lipoxygenase activity
GO:0016702 IDA:UniProtKBFoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019369 IMP:UniProtKBParachidonic acid metabolic process
GO:0046513 ISS:UniProtKBPceramide biosynthetic process
GO:0061436 ISS:UniProtKBPestablishment of skin barrier
GO:0051122 ISS:UniProtKBPhepoxilin biosynthetic process
GO:0043651 ISS:UniProtKBPlinoleic acid metabolic process
GO:0019372 IDA:UniProtKBPlipoxygenase pathway
GO:0055114 IDA:UniProtKBPoxidation-reduction process
GO:0010628 IMP:UniProtKBPpositive regulation of gene expression
GO:0043410 IDA:UniProtKBPpositive regulation of MAPK cascade
GO:0070257 IMP:UniProtKBPpositive regulation of mucus secretion
GO:0006497 ISS:UniProtKBPprotein lipidation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006665 IDA:UniProtKBPsphingolipid metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_150201Synthesis of 12-eicosatetraenoic acid derivatives
SMP Pathway Links
SMP IDDescription
SMP00710Acetaminophen Action Pathway
SMP00083Acetylsalicylic Acid Action Pathway
SMP00692Antipyrine Action Pathway
SMP00693Antrafenine Action Pathway
SMP00075Arachidonic Acid Metabolism
SMP00102Bromfenac Action Pathway
SMP00694Carprofen Action Pathway
SMP00096Celecoxib Action Pathway
SMP00093Diclofenac Action Pathway
SMP00289Diflunisal Action Pathway
SMP00084Etodolac Action Pathway
SMP00695Etoricoxib Action Pathway
SMP00696Fenoprofen Action Pathway
SMP00697Flurbiprofen Action Pathway
SMP00086Ibuprofen Action Pathway
SMP00104Indomethacin Action Pathway
SMP00085Ketoprofen Action Pathway
SMP00098Ketorolac Action Pathway
SMP00353Leukotriene C4 Synthesis Deficiency
SMP00700Lornoxicam Action Pathway
SMP00699Lumiracoxib Action Pathway
SMP00698Magnesium salicylate Action Pathway
SMP00109Mefenamic Acid Action Pathway
SMP00106Meloxicam Action Pathway
SMP00114Nabumetone Action Pathway
SMP00120Naproxen Action Pathway
SMP00702Nepafenac Action Pathway
SMP00113Oxaprozin Action Pathway
SMP00701Phenylbutazone Action Pathway
SMP00077Piroxicam Action Pathway
SMP00087Rofecoxib Action Pathway
SMP00708Salicylate-sodium Action Pathway
SMP00709Salicylic Acid Action Pathway
SMP00707Salsalate Action Pathway
SMP00094Sulindac Action Pathway
SMP00101Suprofen Action Pathway
SMP00706Tenoxicam Action Pathway
SMP00705Tiaprofenic Acid Action Pathway
SMP00704Tolmetin Action Pathway
SMP00703Trisalicylate-choline Action Pathway
SMP00116Valdecoxib Action Pathway
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