MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000133

Ontology/Pathway Information

Entrez Gene ID247
Gene Namearachidonate 15-lipoxygenase, type B
Gene Symbol ALOX15B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005856 IDA:UniProtKBCcytoskeleton
GO:0005829 IDA:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0019898 IDA:UniProtKBCextrinsic component of membrane
GO:0005622 IDA:UniProtKBCintracellular
GO:0016020 IDA:UniProtKBCmembrane
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0050473 IDA:UniProtKBFarachidonate 15-lipoxygenase activity
GO:0036403 IEA:EnsemblFarachidonate 8(S)-lipoxygenase activity
GO:0005509 IDA:UniProtKBFcalcium ion binding
GO:0005506 IDA:UniProtKBFiron ion binding
GO:0016165 IDA:UniProtKBFlinoleate 13S-lipoxygenase activity
GO:0008289 IEA:UniProtKB-KWFlipid binding
GO:0006915 TAS:UniProtKBPapoptotic process
GO:0019369 IDA:UniProtKBParachidonic acid metabolic process
GO:0051122 ISS:UniProtKBPhepoxilin biosynthetic process
GO:0043651 IEA:EnsemblPlinoleic acid metabolic process
GO:0006629 TAS:UniProtKBPlipid metabolic process
GO:0019372 TAS:ReactomePlipoxygenase pathway
GO:0045786 IDA:UniProtKBPnegative regulation of cell cycle
GO:0030336 TAS:UniProtKBPnegative regulation of cell migration
GO:0008285 IDA:UniProtKBPnegative regulation of cell proliferation
GO:0045926 IDA:UniProtKBPnegative regulation of growth
GO:0090197 IMP:UniProtKBPpositive regulation of chemokine secretion
GO:0045618 IEA:EnsemblPpositive regulation of keratinocyte differentiation
GO:0010744 IMP:UniProtKBPpositive regulation of macrophage derived foam cell differentiation
GO:0035360 IEA:EnsemblPpositive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0030850 NAS:UniProtKBPprostate gland development
GO:0030856 NAS:UniProtKBPregulation of epithelial cell differentiation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_150422Synthesis of 15-eicosatetraenoic acid derivatives
SMP Pathway Links
SMP IDDescription
SMP00710Acetaminophen Action Pathway
SMP00083Acetylsalicylic Acid Action Pathway
SMP00692Antipyrine Action Pathway
SMP00693Antrafenine Action Pathway
SMP00075Arachidonic Acid Metabolism
SMP00102Bromfenac Action Pathway
SMP00694Carprofen Action Pathway
SMP00096Celecoxib Action Pathway
SMP00093Diclofenac Action Pathway
SMP00289Diflunisal Action Pathway
SMP00084Etodolac Action Pathway
SMP00695Etoricoxib Action Pathway
SMP00696Fenoprofen Action Pathway
SMP00697Flurbiprofen Action Pathway
SMP00086Ibuprofen Action Pathway
SMP00104Indomethacin Action Pathway
SMP00085Ketoprofen Action Pathway
SMP00098Ketorolac Action Pathway
SMP00353Leukotriene C4 Synthesis Deficiency
SMP00700Lornoxicam Action Pathway
SMP00699Lumiracoxib Action Pathway
SMP00698Magnesium salicylate Action Pathway
SMP00109Mefenamic Acid Action Pathway
SMP00106Meloxicam Action Pathway
SMP00114Nabumetone Action Pathway
SMP00120Naproxen Action Pathway
SMP00702Nepafenac Action Pathway
SMP00113Oxaprozin Action Pathway
SMP00701Phenylbutazone Action Pathway
SMP00077Piroxicam Action Pathway
SMP00087Rofecoxib Action Pathway
SMP00708Salicylate-sodium Action Pathway
SMP00709Salicylic Acid Action Pathway
SMP00707Salsalate Action Pathway
SMP00094Sulindac Action Pathway
SMP00101Suprofen Action Pathway
SMP00706Tenoxicam Action Pathway
SMP00705Tiaprofenic Acid Action Pathway
SMP00704Tolmetin Action Pathway
SMP00703Trisalicylate-choline Action Pathway
SMP00116Valdecoxib Action Pathway
  logo