MGP Database

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MGP000157

Ontology/Pathway Information

Entrez Gene ID316
Gene Namealdehyde oxidase 1
Gene Symbol AOX1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0051537 IEA:UniProtKB-KWF2 iron, 2 sulfur cluster binding
GO:0004031 TAS:ReactomeFaldehyde oxidase activity
GO:0009055 IEA:InterProFelectron carrier activity
GO:0050660 IEA:InterProFflavin adenine dinucleotide binding
GO:0005506 IEA:InterProFiron ion binding
GO:0043546 IEA:InterProFmolybdopterin cofactor binding
GO:0051287 IEA:InterProFNAD binding
GO:0008762 IEA:InterProFUDP-N-acetylmuramate dehydrogenase activity
GO:0004854 TAS:ProtIncFxanthine dehydrogenase activity
GO:0006954 TAS:ProtIncPinflammatory response
GO:0072593 TAS:ProtIncPreactive oxygen species metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0042816 TAS:ReactomePvitamin B6 metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_111217Metabolism
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_25012Vitamins B6 activation to pyridoxal phosphate
SMP Pathway Links
SMP IDDescription
SMP001372-Methyl-3-Hydroxybutryl CoA Dehydrogenase Deficiency
SMP001383-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency
SMP005213-hydroxyisobutyric acid dehydrogenase deficiency
SMP005223-hydroxyisobutyric aciduria
SMP002373-Methylcrotonyl Coa Carboxylase Deficiency Type I
SMP001393-Methylglutaconic Aciduria Type I
SMP001403-Methylglutaconic Aciduria Type III
SMP001413-Methylglutaconic Aciduria Type IV
SMP00427Azathioprine Action Pathway
SMP00173Beta-Ketothiolase Deficiency
SMP00424Citalopram Action Pathway
SMP00627Citalopram Metabolism Pathway
SMP00503Hypophosphatasia
SMP00523Isobutyryl-coa dehydrogenase deficiency
SMP00524Isovaleric acidemia
SMP00238Isovaleric Aciduria
SMP00199Maple Syrup Urine Disease
SMP00428Mercaptopurine Action Pathway
SMP00609Mercaptopurine Metabolism Pathway
SMP00384Methylmalonate Semialdehyde Dehydrogenase Deficiency
SMP00200Methylmalonic Aciduria
SMP00048Nicotinate and Nicotinamide Metabolism
SMP00431Nicotine Action Pathway
SMP00628Nicotine Metabolism Pathway
SMP00236Propionic Acidemia
SMP00430Thioguanine Action Pathway
SMP00063Tryptophan Metabolism
SMP00032Valine, Leucine and Isoleucine Degradation
SMP00017Vitamin B6 Metabolism
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