MGP Database

MGP000168

Record overview

MGPD IDMGP000168
Gene ID336
SpeciesHomo sapiens (Human)
Gene Nameapolipoprotein A-II
Gene Symbol APOA2
SynonymsapoAII; Apo-AII; ApoA-II;
Alternate namesapolipoprotein A-II; apolipoprotein A2;
Chromosome1
Map Location1q23.3
SummaryThis gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for APOA2

Proteins

apolipoprotein A-II preproprotein
Refseq ID:NP_001634
Protein GI:4502149
UniProt ID:P02652
mRNA ID:NM_001643
Length:100
RefSeq Status:
MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQ
 
sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1889
peptide sequence: 
MKLLAATVLLLTICSLEG

mat_peptide: 24..100
product: apolipoprotein A-II
calculated_mol_wt: 8708
peptide sequence: 
QAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQ
 
  logo