MGP Database

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MGP000169

Ontology/Pathway Information

Entrez Gene ID338
Gene Nameapolipoprotein B
Gene Symbol APOB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 IDA:HPACactin cytoskeleton
GO:0042627 IDA:BHF-UCLCchylomicron
GO:0034360 TAS:BHF-UCLCchylomicron remnant
GO:0030669 TAS:ReactomeCclathrin-coated endocytic vesicle membrane
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005769 TAS:ReactomeCearly endosome
GO:0071682 TAS:ReactomeCendocytic vesicle lumen
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0031904 TAS:ReactomeCendosome lumen
GO:0010008 TAS:ReactomeCendosome membrane
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 ISS:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005794 IDA:HPACGolgi apparatus
GO:0034363 IDA:BHF-UCLCintermediate-density lipoprotein particle
GO:0043231 TAS:ProtIncCintracellular membrane-bounded organelle
GO:0034362 IDA:BHF-UCLClow-density lipoprotein particle
GO:0034359 IDA:BHF-UCLCmature chylomicron
GO:0005886 IDA:HPACplasma membrane
GO:0034361 IDA:BHF-UCLCvery-low-density lipoprotein particle
GO:0017127 IMP:BHF-UCLFcholesterol transporter activity
GO:0008201 IDA:BHF-UCLFheparin binding
GO:0035473 IPI:BHF-UCLFlipase binding
GO:0050750 IMP:BHF-UCLFlow-density lipoprotein particle receptor binding
GO:0005543 IDA:BHF-UCLFphospholipid binding
GO:0048844 IEA:EnsemblPartery morphogenesis
GO:0007596 TAS:ReactomePblood coagulation
GO:0071379 IEA:EnsemblPcellular response to prostaglandin stimulus
GO:0071356 IEA:EnsemblPcellular response to tumor necrosis factor
GO:0033344 IEA:EnsemblPcholesterol efflux
GO:0042632 IMP:BHF-UCLPcholesterol homeostasis
GO:0008203 IMP:BHF-UCLPcholesterol metabolic process
GO:0030301 IMP:BHF-UCLPcholesterol transport
GO:0009566 IEA:EnsemblPfertilization
GO:0001701 IEA:EnsemblPin utero embryonic development
GO:0050900 TAS:ReactomePleukocyte migration
GO:0042158 IEA:EnsemblPlipoprotein biosynthetic process
GO:0042159 IEA:EnsemblPlipoprotein catabolic process
GO:0042157 TAS:ReactomePlipoprotein metabolic process
GO:0042953 IEA:EnsemblPlipoprotein transport
GO:0034383 IMP:BHF-UCLPlow-density lipoprotein particle clearance
GO:0034374 IMP:BHF-UCLPlow-density lipoprotein particle remodeling
GO:0007399 IEA:EnsemblPnervous system development
GO:0007603 TAS:ReactomePphototransduction, visible light
GO:0010886 IDA:BHF-UCLPpositive regulation of cholesterol storage
GO:0010884 IDA:BHF-UCLPpositive regulation of lipid storage
GO:0010744 IDA:BHF-UCLPpositive regulation of macrophage derived foam cell differentiation
GO:0009791 IEA:EnsemblPpost-embryonic development
GO:0006898 TAS:ReactomePreceptor-mediated endocytosis
GO:0045540 IEA:EnsemblPregulation of cholesterol biosynthetic process
GO:0009743 IEA:EnsemblPresponse to carbohydrate
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0010269 IEA:EnsemblPresponse to selenium ion
GO:0009615 IEP:UniProtKBPresponse to virus
GO:0001523 TAS:ReactomePretinoid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007283 IEA:EnsemblPspermatogenesis
GO:0030317 IEA:EnsemblPsperm motility
GO:0019433 IEA:EnsemblPtriglyceride catabolic process
GO:0006642 IEA:EnsemblPtriglyceride mobilization
GO:0034379 IC:BHF-UCLPvery-low-density lipoprotein particle assembly
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_160300Binding and Uptake of Ligands by Scavenger Receptors
REACT_12051Cell surface interactions at the vascular wall
REACT_6841Chylomicron-mediated lipid transport
REACT_116125Disease
REACT_160102Diseases associated with visual transduction
REACT_604Hemostasis
REACT_6934LDL-mediated lipid transport
REACT_602Lipid digestion, mobilization, and transport
REACT_6823Lipoprotein metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_268444Orphan transporters
REACT_23876Platelet homeostasis
REACT_23879Platelet sensitization by LDL
REACT_24968Retinoid metabolism and transport
REACT_163699Scavenging by Class A Receptors
REACT_163679Scavenging by Class B Receptors
REACT_163813Scavenging by Class F Receptors
REACT_164002Scavenging by Class H Receptors
REACT_111102Signal Transduction
REACT_15518Transmembrane transport of small molecules
REACT_160125Visual phototransduction
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