MGP Database

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MGP000176

Record overview

MGPD IDMGP000176
Gene ID351
SpeciesHomo sapiens (Human)
Gene Nameamyloid beta (A4) precursor protein
Gene Symbol APP
SynonymsAAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
Alternate namesamyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); alzheimer disease amyloid protein; cerebral vascular amyloid peptide;
Chromosome21
Map Location21q21.3
SummaryThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
OrthologsView orthologs and multiple alignments for APP

Proteins

amyloid beta A4 protein isoform a precursor
Refseq ID:NP_000475
Protein GI:4502167
UniProt ID:P05067
mRNA ID:NM_000484
Length:770
RefSeq Status:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR
GRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSAD
AEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC
RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEA
KHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRA
EQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
KTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG
AIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..733
product: amyloid beta A4 protein isoform i
calculated_mol_wt: 81153
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
GSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQ
NGYENPTYKFFEQMQN

mat_peptide: 635..676
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 635..674
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..677
product: amyloid beta A4 protein isoform j
calculated_mol_wt: 74997
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGV
VIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 579..620
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 579..618
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..714
product: amyloid beta A4 protein isoform f
calculated_mol_wt: 79071
peptide sequence: 
LEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP
CGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIA
TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPD
AVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLAL
ENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDA
EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 616..657
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 616..655
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 648..689
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 648..687
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 562..603
product: amyloid beta A4 protein isoform g
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 562..601
product: amyloid beta A4 protein isoform g
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..639
product: amyloid beta A4 protein isoform e
calculated_mol_wt: 70790
peptide sequence: 
LEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP
CGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIA
TTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAAN
ERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLL
YNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADR
GLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERH
LSKMQQNGYENPTYKFFEQMQN

mat_peptide: 541..582
product: amyloid beta A4 protein isoform e
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 541..580
product: amyloid beta A4 protein isoform e
experiment: DESCRIPTION:antimicrobial peptide[20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..770
product: amyloid beta A4 protein isoform a
calculated_mol_wt: 85181
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIV
ITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..687
product: Soluble APP-alpha
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 75989
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQK

mat_peptide: 18..671
product: Soluble APP-beta
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 74052
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKM

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 672..770
product: C99
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 11147
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 672..713
product: amyloid beta A4 protein isoform a
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 672..711
product: amyloid beta A4 protein isoform a
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 688..770
product: C83
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 9210
peptide sequence: 
LVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 688..713
product: P3(42)
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 2577
peptide sequence: 
LVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 688..711
product: P3(40)
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 2393
peptide sequence: 
LVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 691..770
product: C80
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 8850
peptide sequence: 
FAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 712..770
product: Gamma-secretase C-terminal fragment 59
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 6835
peptide sequence: 
IATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 714..770
product: Gamma-secretase C-terminal fragment 57
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 6651
peptide sequence: 
TVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 721..770
product: Gamma-secretase C-terminal fragment 50 (By similarity)
inference: non-experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 5911
peptide sequence: 
VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 740..770
product: C31
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 3717
peptide sequence: 
AAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
amyloid beta A4 protein isoform b precursor
Refseq ID:NP_958816
Protein GI:41406055
UniProt ID:P05067
mRNA ID:NM_201413
Length:751
RefSeq Status:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR
GRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSAD
AEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC
RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQ
AKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVD
PKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ
PWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT
LVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform c precursor
Refseq ID:NP_958817
Protein GI:41406057
UniProt ID:P05067
mRNA ID:NM_201414
Length:695
RefSeq Status:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR
GRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSAD
AEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAV
DKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALEN
YITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDD
VLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEF
RHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform d
Refseq ID:NP_001129488
Protein GI:209862833
UniProt ID:P05067
mRNA ID:NM_001136016
Length:746
RefSeq Status:
MDQLEDLLVLFINYVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQC
KTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDD
SDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMIS
RWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLP
KADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAA
QIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSF
GADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLK
KKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..733
product: amyloid beta A4 protein isoform i
calculated_mol_wt: 81153
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
GSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQ
NGYENPTYKFFEQMQN

mat_peptide: 635..676
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 635..674
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..677
product: amyloid beta A4 protein isoform j
calculated_mol_wt: 74997
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGV
VIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 579..620
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 579..618
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..714
product: amyloid beta A4 protein isoform f
calculated_mol_wt: 79071
peptide sequence: 
LEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP
CGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIA
TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPD
AVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLAL
ENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDA
EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 616..657
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 616..655
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 648..689
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 648..687
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform e precursor
Refseq ID:NP_001129601
Protein GI:209915570
UniProt ID:P05067
mRNA ID:NM_001136129
Length:639
RefSeq Status:
MLPGLALLLLAAWTARALEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKE
TCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEE
EAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAV
IQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVM
THLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPA
NTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSI
HHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..733
product: amyloid beta A4 protein isoform i
calculated_mol_wt: 81153
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
GSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQ
NGYENPTYKFFEQMQN

mat_peptide: 635..676
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 635..674
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..677
product: amyloid beta A4 protein isoform j
calculated_mol_wt: 74997
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGV
VIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 579..620
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 579..618
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..714
product: amyloid beta A4 protein isoform f
calculated_mol_wt: 79071
peptide sequence: 
LEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP
CGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIA
TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPD
AVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLAL
ENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDA
EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 616..657
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 616..655
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 648..689
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 648..687
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 562..603
product: amyloid beta A4 protein isoform g
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 562..601
product: amyloid beta A4 protein isoform g
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..639
product: amyloid beta A4 protein isoform e
calculated_mol_wt: 70790
peptide sequence: 
LEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP
CGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIA
TTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAAN
ERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLL
YNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADR
GLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERH
LSKMQQNGYENPTYKFFEQMQN

mat_peptide: 541..582
product: amyloid beta A4 protein isoform e
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 541..580
product: amyloid beta A4 protein isoform e
experiment: DESCRIPTION:antimicrobial peptide[20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform f precursor
Refseq ID:NP_001129602
Protein GI:209915573
UniProt ID:P05067
mRNA ID:NM_001136130
Length:714
RefSeq Status:
MLPGLALLLLAAWTARALEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKE
TCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEE
EAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEP
LARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVET
HMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAE
EIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGS
GLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNG
YENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..733
product: amyloid beta A4 protein isoform i
calculated_mol_wt: 81153
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
GSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQ
NGYENPTYKFFEQMQN

mat_peptide: 635..676
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 635..674
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..677
product: amyloid beta A4 protein isoform j
calculated_mol_wt: 74997
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGV
VIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 579..620
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 579..618
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..714
product: amyloid beta A4 protein isoform f
calculated_mol_wt: 79071
peptide sequence: 
LEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP
CGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIA
TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPD
AVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLAL
ENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDA
EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 616..657
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 616..655
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform g
Refseq ID:NP_001129603
Protein GI:209915575
UniProt ID:P05067
mRNA ID:NM_001136131
Length:660
RefSeq Status:
MFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKF
LHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVA
EVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVM
REWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLK
HFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGV
VIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..733
product: amyloid beta A4 protein isoform i
calculated_mol_wt: 81153
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
GSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQ
NGYENPTYKFFEQMQN

mat_peptide: 635..676
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 635..674
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..677
product: amyloid beta A4 protein isoform j
calculated_mol_wt: 74997
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGV
VIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 579..620
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 579..618
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..714
product: amyloid beta A4 protein isoform f
calculated_mol_wt: 79071
peptide sequence: 
LEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP
CGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIA
TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPD
AVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLAL
ENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDA
EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 616..657
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 616..655
product: amyloid beta A4 protein isoform f
experiment: DESCRIPTION:antimicrobial peptide[20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 648..689
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 648..687
product: amyloid beta A4 protein isoform d
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

mat_peptide: 562..603
product: amyloid beta A4 protein isoform g
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 562..601
product: amyloid beta A4 protein isoform g
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform h precursor
Refseq ID:NP_001191230
Protein GI:324021738
UniProt ID:P05067
mRNA ID:NM_001204301
Length:752
RefSeq Status:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR
GRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSAD
AEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC
RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEA
KHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRA
EQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
KTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVI
TLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform i precursor
Refseq ID:NP_001191231
Protein GI:324021736
UniProt ID:P05067
mRNA ID:NM_001204302
Length:733
RefSeq Status:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR
GRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSAD
AEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC
RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQ
AKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVD
PKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ
PWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVE
VDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..733
product: amyloid beta A4 protein isoform i
calculated_mol_wt: 81153
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
GSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQ
NGYENPTYKFFEQMQN

mat_peptide: 635..676
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 635..674
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
amyloid beta A4 protein isoform j precursor
Refseq ID:NP_001191232
Protein GI:324021740
UniProt ID:P05067
mRNA ID:NM_001204303
Length:677
RefSeq Status:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR
GRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSAD
AEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAV
DKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALEN
YITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDD
VLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAE
DVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..695
product: amyloid beta A4 protein isoform c
calculated_mol_wt: 76900
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFA
EDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 597..638
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 597..636
product: amyloid beta A4 protein isoform c
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..751
product: amyloid beta A4 protein isoform b
calculated_mol_wt: 83056
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
VEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVV
EVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 653..694
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 653..692
product: amyloid beta A4 protein isoform b
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..752
product: amyloid beta A4 protein isoform h
calculated_mol_wt: 83277
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAE
RQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRM
VDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDD
LQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 654..695
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 654..693
product: amyloid beta A4 protein isoform h
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..733
product: amyloid beta A4 protein isoform i
calculated_mol_wt: 81153
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCA
PFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQ
EKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRV
IYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE
GSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQ
NGYENPTYKFFEQMQN

mat_peptide: 635..676
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 635..674
product: amyloid beta A4 protein isoform i
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1781
peptide sequence: 
MLPGLALLLLAAWTARA

mat_peptide: 18..677
product: amyloid beta A4 protein isoform j
calculated_mol_wt: 74997
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQ
KAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN
MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDA
LMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGV
VIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

mat_peptide: 18..286
product: N-APP
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P05067.3)
calculated_mol_wt: 30196
peptide sequence: 
LEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRC
LVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDY
ADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEV

mat_peptide: 579..620
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
exception: alternative processing
calculated_mol_wt: 4514
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

mat_peptide: 579..618
product: amyloid beta A4 protein isoform j
experiment: DESCRIPTION:antimicrobial peptide[PMID: 20209079]
calculated_mol_wt: 4330
peptide sequence: 
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
 
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