MGP Database

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MGP000177

Ontology/Pathway Information

Entrez Gene ID353
Gene Nameadenine phosphoribosyltransferase
Gene Symbol APRT
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005634 IDA:HPACnucleus
GO:0002055 IEA:EnsemblFadenine binding
GO:0003999 TAS:ReactomeFadenine phosphoribosyltransferase activity
GO:0016208 IDA:MGIFAMP binding
GO:0006168 IEA:EnsemblPadenine salvage
GO:0044209 IEA:UniProtKB-UniPathwayPAMP salvage
GO:0032869 IEA:EnsemblPcellular response to insulin stimulus
GO:0007625 IEA:EnsemblPgrooming behavior
GO:0007595 IEA:EnsemblPlactation
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0043101 TAS:ReactomePpurine-containing compound salvage
GO:0006144 TAS:ReactomePpurine nucleobase metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_522Purine metabolism
REACT_1923Purine salvage
SMP Pathway Links
SMP IDDescription
SMP00535Adenine phosphoribosyltransferase deficiency (APRT)
SMP00144Adenosine Deaminase Deficiency
SMP00167Adenylosuccinate Lyase Deficiency
SMP00168AICA-Ribosiduria
SMP00427Azathioprine Action Pathway
SMP00365Gout or Kelley-Seegmiller Syndrome
SMP00364Lesch-Nyhan Syndrome (LNS)
SMP00428Mercaptopurine Action Pathway
SMP00536Mitochondrial DNA depletion syndrome
SMP00203Molybdenum Cofactor Deficiency
SMP00537Myoadenylate deaminase deficiency
SMP00050Purine Metabolism
SMP00210Purine Nucleoside Phosphorylase Deficiency
SMP00430Thioguanine Action Pathway
SMP00220Xanthine Dehydrogenase Deficiency (Xanthinuria)
SMP00512Xanthinuria type I
SMP00513Xanthinuria type II
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