MGP Database

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MGP000182

Ontology/Pathway Information

Entrez Gene ID359
Gene Nameaquaporin 2 (collecting duct)
Gene Symbol AQP2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IDA:UniProtKBCapical plasma membrane
GO:0016323 IEA:UniProtKB-SubCellCbasolateral plasma membrane
GO:0030136 IEA:EnsemblCclathrin-coated vesicle
GO:0005769 IEA:EnsemblCearly endosome
GO:0070382 IEA:EnsemblCexocytic vesicle
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0005764 IEA:EnsemblClysosome
GO:0016020 IDA:MGICmembrane
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0043234 IEA:EnsemblCprotein complex
GO:0055037 IEA:EnsemblCrecycling endosome
GO:0005791 IEA:EnsemblCrough endoplasmic reticulum
GO:0005802 IEA:EnsemblCtrans-Golgi network
GO:0030658 TAS:ReactomeCtransport vesicle membrane
GO:0015168 IDA:UniProtKBFglycerol transmembrane transporter activity
GO:0015250 EXP:ReactomeFwater channel activity
GO:0005372 IDA:UniProtKBFwater transmembrane transporter activity
GO:0030042 IEA:EnsemblPactin filament depolymerization
GO:0007568 IEA:EnsemblPaging
GO:0006915 IEA:EnsemblPapoptotic process
GO:0071280 IDA:UniProtKBPcellular response to copper ion
GO:0071288 IDA:UniProtKBPcellular response to mercury ion
GO:0042631 IEA:EnsemblPcellular response to water deprivation
GO:0006884 IEA:EnsemblPcell volume homeostasis
GO:0007588 TAS:ProtIncPexcretion
GO:0007565 IEA:EnsemblPfemale pregnancy
GO:0015793 IDA:UniProtKBPglycerol transport
GO:0006972 IEA:EnsemblPhyperosmotic response
GO:0072205 IEA:EnsemblPmetanephric collecting duct development
GO:0051928 IEA:EnsemblPpositive regulation of calcium ion transport
GO:0003097 IEA:EnsemblPrenal water transport
GO:0051592 IEA:EnsemblPresponse to calcium ion
GO:0033762 IEA:EnsemblPresponse to glucagon
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0010226 IEA:EnsemblPresponse to lithium ion
GO:0009651 IEA:EnsemblPresponse to salt stress
GO:0042594 IEA:EnsemblPresponse to starvation
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006833 IDA:UniProtKBPwater transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_23887Aquaporin-mediated transport
REACT_23826Passive transport by Aquaporins
REACT_15518Transmembrane transport of small molecules
REACT_24023Vasopressin regulates renal water homeostasis via Aquaporins
SMP Pathway Links
SMP IDDescription
SMP00133Amiloride Action Pathway
SMP00090Bendroflumethiazide Action Pathway
SMP00583Blue diaper syndrome
SMP00088Bumetanide Action Pathway
SMP00078Chlorothiazide Action Pathway
SMP00122Chlorthalidone Action Pathway
SMP00103Cyclothiazide Action Pathway
SMP00723Cystinuria
SMP00135Eplerenone Action Pathway
SMP00097Ethacrynic Acid Action Pathway
SMP00115Furosemide Action Pathway
SMP00245Glucose Transporter Defect (SGLT2)
SMP00189Hartnup Disorder
SMP00100Hydrochlorothiazide Action Pathway
SMP00108Hydroflumethiazide Action Pathway
SMP00193Iminoglycinuria
SMP00584Iminoglycinuria
SMP00110Indapamide Action Pathway
SMP00483Kidney Function
SMP00197Lysinuric Protein Intolerance
SMP00585Lysinuric protein intolerance (LPI)
SMP00081Methyclothiazide Action Pathway
SMP00105Metolazone Action Pathway
SMP00080Polythiazide Action Pathway
SMP00091Quinethazone Action Pathway
SMP00184Renal Glucosuria
SMP00134Spironolactone Action Pathway
SMP00118Torsemide Action Pathway
SMP00132Triamterene Action Pathway
SMP00121Trichlormethiazide Action Pathway
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