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MGP000183

Record overview

MGPD IDMGP000183
Gene ID360
SpeciesHomo sapiens (Human)
Gene Nameaquaporin 3 (Gill blood group)
Gene Symbol AQP3
SynonymsGIL; AQP-3;
Alternate namesaquaporin-3; aquaglyceroporin-3; aquaporin 3 (GIL blood group);
Chromosome9
Map Location9p13
SummaryThis gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. [provided by RefSeq, Aug 2011]
OrthologsView orthologs and multiple alignments for AQP3

Proteins

aquaporin-3
Refseq ID:NP_004916
Protein GI:4826645
UniProt ID:Q92482
mRNA ID:NM_004925
Length:292
RefSeq Status:
MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIK
LPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVL
VIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI
 
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