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MGP000259

Record overview

MGPD IDMGP000259
Gene ID515
SpeciesHomo sapiens (Human)
Gene NameATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
Gene Symbol ATP5F1
SynonymsPIG47;
Alternate namesATP synthase F(0) complex subunit B1, mitochondrial; ATP synthase B chain, mitochondrial; ATP synthase proton-transporting mitochondrial F(0) complex subunit B1; ATP synthase subunit b, mitochondrial; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1; ATPase subunit b; H+-ATP synthase subunit b; cell proliferation-inducing protein 47;
Chromosome1
Map Location1p13.2
SummaryThis gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the b subunit of the proton channel. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ATP5F1

Proteins

ATP synthase F(0) complex subunit B1, mitochondrial precursor
Refseq ID:NP_001679
Protein GI:21361565
UniProt ID:P24539
mRNA ID:NM_001688
Length:256
RefSeq Status:
MLSRVVLSAAATAAPSLKNAAFLGPGVLQATRTFHTGQPHLVPVPPLPEYGGKVRYGLIPEEFFQFLYPKTGVTGPYVLGTGLILYALSKEIYVISAETF
TALSVLGVMVYGIKKYGPFVADFADKLNEQKLAQLEEAKQASIQHIQNAIDTEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLYRVYKEVKNRLDYH
ISVQNMMRRKEQEHMINWVEKHVVQSISTQQEKETIAKCIADLKLLAKKAQAQPVM
 
transit_peptide: 1..42
calculated_mol_wt: 4301
peptide sequence: 
MLSRVVLSAAATAAPSLKNAAFLGPGVLQATRTFHTGQPHLV

mat_peptide: 43..256
product: ATP synthase F(0) complex subunit B1, mitochondrial
calculated_mol_wt: 24626
peptide sequence: 
PVPPLPEYGGKVRYGLIPEEFFQFLYPKTGVTGPYVLGTGLILYALSKEIYVISAETFTALSVLGVMVYGIKKYGPFVADFADKLNEQKLAQLEEAKQAS
IQHIQNAIDTEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLYRVYKEVKNRLDYHISVQNMMRRKEQEHMINWVEKHVVQSISTQQEKETIAKCIAD
LKLLAKKAQAQPVM
 
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