MGP Database

MGP000283

Ontology/Pathway Information

Entrez Gene ID	558
Gene Name	AXL receptor tyrosine kinase
Gene Symbol	AXL
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IDA:UniProtKB	C	cell surface
GO:0005615	IDA:UniProtKB	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005887	TAS:ProtInc	C	integral component of plasma membrane
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0001786	IDA:UniProtKB	F	phosphatidylserine binding
GO:0004714	TAS:ProtInc	F	transmembrane receptor protein tyrosine kinase activity
GO:0043277	IEA:Ensembl	P	apoptotic cell clearance
GO:0001974	IEA:Ensembl	P	blood vessel remodeling
GO:0048469	IEP:UniProtKB	P	cell maturation
GO:0031668	IEA:Ensembl	P	cellular response to extracellular stimulus
GO:0070301	IEA:Ensembl	P	cellular response to hydrogen peroxide
GO:0035457	IDA:UniProtKB	P	cellular response to interferon-alpha
GO:0071222	IDA:UniProtKB	P	cellular response to lipopolysaccharide
GO:0097028	IEP:UniProtKB	P	dendritic cell differentiation
GO:0007167	IEA:Ensembl	P	enzyme linked receptor protein signaling pathway
GO:0034101	IEA:Ensembl	P	erythrocyte homeostasis
GO:0021885	IEA:Ensembl	P	forebrain cell migration
GO:0006954	IEA:Ensembl	P	inflammatory response
GO:0045087	IEA:UniProtKB-KW	P	innate immune response
GO:0001779	IEA:Ensembl	P	natural killer cell differentiation
GO:2000669	IDA:UniProtKB	P	negative regulation of dendritic cell apoptotic process
GO:0032689	IDA:UniProtKB	P	negative regulation of interferon-gamma production
GO:0051250	IEA:Ensembl	P	negative regulation of lymphocyte activation
GO:0043524	IEA:Ensembl	P	negative regulation of neuron apoptotic process
GO:0032720	IEA:Ensembl	P	negative regulation of tumor necrosis factor production
GO:0001764	IEA:Ensembl	P	neuron migration
GO:0031100	IEA:Ensembl	P	organ regeneration
GO:0042698	IEA:Ensembl	P	ovulation cycle
GO:0018108	TAS:GOC	P	peptidyl-tyrosine phosphorylation
GO:0006909	IDA:UniProtKB	P	phagocytosis
GO:0030168	IEA:Ensembl	P	platelet activation
GO:0001961	IDA:UniProtKB	P	positive regulation of cytokine-mediated signaling pathway
GO:0032825	IDA:UniProtKB	P	positive regulation of natural killer cell differentiation
GO:0051897	IEA:Ensembl	P	positive regulation of protein kinase B signaling
GO:0043491	IEA:Ensembl	P	protein kinase B signaling
GO:0032940	IEA:Ensembl	P	secretion by cell
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0007283	IEA:Ensembl	P	spermatogenesis
GO:0034446	IEA:Ensembl	P	substrate adhesion-dependent cell spreading
GO:0060068	IEA:Ensembl	P	vagina development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_12529	Signaling by VEGF
REACT_111102	Signal Transduction
REACT_264464	VEGFA-VEGFR2 Pathway