MGP Database

MGP000303

Ontology/Pathway Information

Entrez Gene ID	613
Gene Name	breakpoint cluster region
Gene Symbol	BCR
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	TAS:Reactome	C	cytosol
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0016020	IDA:UniProtKB	C	membrane
GO:0005886	IEA:Ensembl	C	plasma membrane
GO:0043234	IDA:MGI	C	protein complex
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0005096	TAS:ProtInc	F	GTPase activator activity
GO:0016301	TAS:Reactome	F	kinase activity
GO:0004674	TAS:ProtInc	F	protein serine/threonine kinase activity
GO:0004713	TAS:Reactome	F	protein tyrosine kinase activity
GO:0030675	IEA:Ensembl	F	Rac GTPase activator activity
GO:0005089	IEA:InterPro	F	Rho guanyl-nucleotide exchange factor activity
GO:0030036	IEA:Ensembl	P	actin cytoskeleton organization
GO:0007420	IEA:Ensembl	P	brain development
GO:0042472	IEA:Ensembl	P	inner ear morphogenesis
GO:0030336	IEA:Ensembl	P	negative regulation of cell migration
GO:0050728	IEA:Ensembl	P	negative regulation of inflammatory response
GO:0043314	IEA:Ensembl	P	negative regulation of neutrophil degranulation
GO:0050885	IEA:Ensembl	P	neuromuscular process controlling balance
GO:0018108	TAS:GOC	P	peptidyl-tyrosine phosphorylation
GO:0048008	IEA:Ensembl	P	platelet-derived growth factor receptor signaling pathway
GO:0050766	IEA:Ensembl	P	positive regulation of phagocytosis
GO:0046777	IEA:Ensembl	P	protein autophosphorylation
GO:0006468	TAS:ProtInc	P	protein phosphorylation
GO:0051726	IEA:Ensembl	P	regulation of cell cycle
GO:0051056	TAS:Reactome	P	regulation of small GTPase mediated signal transduction
GO:0032496	IEA:Ensembl	P	response to lipopolysaccharide
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0007264	TAS:Reactome	P	small GTPase mediated signal transduction

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_116125	Disease
REACT_11051	Rho GTPase cycle
REACT_121141	Signaling by FGFR1 fusion mutants
REACT_120999	Signaling by FGFR1 mutants
REACT_120736	Signaling by FGFR in disease
REACT_121398	Signaling by FGFR mutants
REACT_11044	Signaling by Rho GTPases
REACT_111102	Signal Transduction