MGP Database

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MGP000305

UniProt Annotations

Entry Information
Gene Name3-hydroxybutyrate dehydrogenase, type 1
Protein EntryBDH_HUMAN
UniProt IDQ02338
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity(R)-3-hydroxybutanoate + NAD(+) = acetoacetate + NADH.
Enzyme RegulationRequires phosphatidylcholine as an allosteric activator for enzymatic activity.
Sequence CautionSequence=AAA58352.1; Type=Frameshift; Positions=124, 134; Evidence={ECO:0000305};
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. {ECO:0000305}.
Subcellular LocationMitochondrion matrix.
SubunitHomotetramer.
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