MGP Database

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MGP000317

Record overview

MGPD IDMGP000317
Gene ID644
SpeciesHomo sapiens (Human)
Gene Namebiliverdin reductase A
Gene Symbol BLVRA
SynonymsBVR; BLVR; BVRA;
Alternate namesbiliverdin reductase A; BVR A; biliverdin-IX alpha-reductase;
Chromosome7
Map Location7p13
EC Number1.3.1.24
SummaryThe protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]
OrthologsView orthologs and multiple alignments for BLVRA

Proteins

biliverdin reductase A precursor
Refseq ID:NP_000703
Protein GI:33589854
UniProt ID:P53004
mRNA ID:NM_000712
Length:296
RefSeq Status:
MNAEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPM
TLSLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLVSATLEERKEDQYMK
MTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVNKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK
 
mat_peptide: 3..296
product: Biliverdin reductase A
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P53004.2)
calculated_mol_wt: 33183
peptide sequence: 
AEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTL
SLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLVSATLEERKEDQYMKMT
VCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVNKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK
 
biliverdin reductase A precursor
Refseq ID:NP_001240752
Protein GI:359465572
UniProt ID:P53004
mRNA ID:NM_001253823
Length:296
RefSeq Status:
Protein sequence is identical to GI:33589854 (mRNA isoform)
 
mat_peptide: 3..296
product: Biliverdin reductase A
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P53004.2)
calculated_mol_wt: 33183
peptide sequence: 
AEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTL
SLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLVSATLEERKEDQYMKMT
VCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVNKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK

mat_peptide: 3..296
product: Biliverdin reductase A
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P53004.2)
calculated_mol_wt: 33183
peptide sequence: 
AEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTL
SLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLVSATLEERKEDQYMKMT
VCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVNKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK
 
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