MGP Database

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MGP000326

Ontology/Pathway Information

Entrez Gene ID659
Gene Namebone morphogenetic protein receptor, type II (serine/threonine kinase)
Gene Symbol BMPR2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IEA:EnsemblCapical plasma membrane
GO:0009925 IEA:EnsemblCbasal plasma membrane
GO:0005901 IEA:EnsemblCcaveola
GO:0009986 IEA:EnsemblCcell surface
GO:0005737 IEA:EnsemblCcytoplasm
GO:0030425 IEA:EnsemblCdendrite
GO:0005615 IDA:UniProtKBCextracellular space
GO:0044214 TAS:AgBaseCfully spanning plasma membrane
GO:0005887 IDA:BHF-UCLCintegral component of plasma membrane
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0016362 TAS:ReactomeFactivin receptor activity, type II
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004702 IEA:InterProFreceptor signaling protein serine/threonine kinase activity
GO:0005024 IEA:InterProFtransforming growth factor beta-activated receptor activity
GO:0032924 TAS:GOCPactivin receptor signaling pathway
GO:0009952 ISS:BHF-UCLPanterior/posterior pattern specification
GO:0060840 ISS:BHF-UCLPartery development
GO:0001974 ISS:BHF-UCLPblood vessel remodeling
GO:0030509 IDA:BHF-UCLPBMP signaling pathway
GO:0007420 IEA:EnsemblPbrain development
GO:0009267 IEP:BHF-UCLPcellular response to starvation
GO:0002063 IMP:AgBasePchondrocyte development
GO:0060173 IEA:EnsemblPlimb development
GO:0048286 ISS:BHF-UCLPlung alveolus development
GO:0001946 ISS:BHF-UCLPlymphangiogenesis
GO:0060836 ISS:BHF-UCLPlymphatic endothelial cell differentiation
GO:0001707 ISS:BHF-UCLPmesoderm formation
GO:0030308 IDA:UniProtKBPnegative regulation of cell growth
GO:1902731 IMP:AgBasePnegative regulation of chondrocyte proliferation
GO:2000279 IMP:BHF-UCLPnegative regulation of DNA biosynthetic process
GO:0003085 IMP:BHF-UCLPnegative regulation of systemic arterial blood pressure
GO:0045906 ISS:BHF-UCLPnegative regulation of vasoconstriction
GO:0048842 IEA:EnsemblPpositive regulation of axon extension involved in axon guidance
GO:0030513 IMP:UniProtKBPpositive regulation of BMP signaling pathway
GO:0030501 IMP:BHF-UCLPpositive regulation of bone mineralization
GO:0010595 IMP:UniProtKBPpositive regulation of endothelial cell migration
GO:0001938 IMP:UniProtKBPpositive regulation of endothelial cell proliferation
GO:0010634 IDA:UniProtKBPpositive regulation of epithelial cell migration
GO:0045669 IMP:BHF-UCLPpositive regulation of osteoblast differentiation
GO:0010862 IMP:UniProtKBPpositive regulation of pathway-restricted SMAD protein phosphorylation
GO:0042127 IMP:HGNCPregulation of cell proliferation
GO:0014916 IMP:BHF-UCLPregulation of lung blood pressure
GO:0061298 ISS:BHF-UCLPretina vasculature development in camera-type eye
GO:0006366 IMP:BHF-UCLPtranscription from RNA polymerase II promoter
GO:0007178 IDA:BHF-UCLPtransmembrane receptor protein serine/threonine kinase signaling pathway
GO:0048010 ISS:BHF-UCLPvascular endothelial growth factor receptor signaling pathway
GO:0060841 ISS:BHF-UCLPvenous blood vessel development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_12034Signaling by BMP
REACT_111102Signal Transduction
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