MGP Database

MGP000346

Record overview

MGPD IDMGP000346
Gene ID708
SpeciesHomo sapiens (Human)
Gene Namecomplement component 1, q subcomponent binding protein
Gene Symbol C1QBP
Synonymsp32; HABP1; gC1qR; GC1QBP; SF2p32; gC1Q-R;
Alternate namescomplement component 1 Q subcomponent-binding protein, mitochondrial; ASF/SF2-associated protein p32; C1q globular domain-binding protein; glycoprotein gC1qBP; hyaluronan-binding protein 1; mitochondrial matrix protein p32; p33; splicing factor SF2-associated protein;
Chromosome17
Map Location17p13.3
SummaryThe human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for C1QBP

Proteins

complement component 1 Q subcomponent-binding protein, mitochondrial precursor
Refseq ID:NP_001203
Protein GI:4502491
UniProt ID:Q07021
mRNA ID:NM_001212
Length:282
RefSeq Status:
MLPLLRCVPRVLGSSVAGLRAAAPASPFRQLLQPAPRLCTRPFGLLSVRAGSERRPGLLRPRGPCACGCGCGSLHTDGDKAFVDFLSDEIKEERKIQKHK
TLPKMSGGWELELNGTEAKLVRKVAGEKITVTFNINNSIPPTFDGEEEPSQGQKVEEQEPELTSTPNFVVEVIKNDDGKKALVLDCHYPEDEVGQEDEAE
SDIFSIREVSFQSTGESEWKDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ
 
transit_peptide: 1..73
calculated_mol_wt: 7597
peptide sequence: 
MLPLLRCVPRVLGSSVAGLRAAAPASPFRQLLQPAPRLCTRPFGLLSVRAGSERRPGLLRPRGPCACGCGCGS

mat_peptide: 74..282
product: complement component 1 Q subcomponent-binding protein, mitochondrial
calculated_mol_wt: 23783
peptide sequence: 
LHTDGDKAFVDFLSDEIKEERKIQKHKTLPKMSGGWELELNGTEAKLVRKVAGEKITVTFNINNSIPPTFDGEEEPSQGQKVEEQEPELTSTPNFVVEVI
KNDDGKKALVLDCHYPEDEVGQEDEAESDIFSIREVSFQSTGESEWKDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLE
DLKSFVKSQ
 
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