MGP Database

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MGP000352

Ontology/Pathway Information

Entrez Gene ID716
Gene Namecomplement component 1, s subcomponent
Gene Symbol C1S
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0072562 IDA:UniProtKBCblood microparticle
GO:0005576 TAS:ReactomeCextracellular region
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005509 IEA:InterProFcalcium ion binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0004252 IDA:UniProtKBFserine-type endopeptidase activity
GO:0006956 TAS:ReactomePcomplement activation
GO:0006958 TAS:ReactomePcomplement activation, classical pathway
GO:0045087 TAS:ReactomePinnate immune response
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_7956Classical antibody-mediated complement activation
REACT_6932Complement cascade
REACT_8012Creation of C4 and C2 activators
REACT_6900Immune System
REACT_8024Initial triggering of complement
REACT_6802Innate Immune System
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