MGP Database

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MGP000379

Ontology/Pathway Information

Entrez Gene ID773
Gene Namecalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Gene Symbol CACNA1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0042995 IDA:UniProtKBCcell projection
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0030425 IEA:EnsemblCdendrite
GO:0016021 NAS:UniProtKBCintegral component of membrane
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0005891 IEA:EnsemblCvoltage-gated calcium channel complex
GO:0008331 IBA:RefGenomeFhigh voltage-gated calcium channel activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0019905 IDA:UniProtKBFsyntaxin binding
GO:0005245 IDA:UniProtKBFvoltage-gated calcium channel activity
GO:0007628 IEA:EnsemblPadult walking behavior
GO:0048266 IEA:EnsemblPbehavioral response to pain
GO:0017156 IEA:EnsemblPcalcium ion-dependent exocytosis
GO:0048791 IEA:EnsemblPcalcium ion-dependent exocytosis of neurotransmitter
GO:0070509 IBA:RefGenomePcalcium ion import
GO:0008219 IDA:UniProtKBPcell death
GO:0016049 IEA:EnsemblPcell growth
GO:0030644 IEA:EnsemblPcellular chloride ion homeostasis
GO:0021679 IEA:EnsemblPcerebellar molecular layer development
GO:0021702 IEA:EnsemblPcerebellar Purkinje cell differentiation
GO:0021590 IEA:EnsemblPcerebellum maturation
GO:0048813 IEA:EnsemblPdendrite morphogenesis
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0014051 IEA:EnsemblPgamma-aminobutyric acid secretion
GO:0007214 IEA:EnsemblPgamma-aminobutyric acid signaling pathway
GO:0006006 IEA:EnsemblPglucose metabolic process
GO:0042445 IEA:EnsemblPhormone metabolic process
GO:0051899 TAS:ReactomePmembrane depolarization
GO:0086010 IBA:RefGenomePmembrane depolarization during action potential
GO:0050883 IEA:EnsemblPmusculoskeletal movement, spinal reflex action
GO:0032353 IEA:EnsemblPnegative regulation of hormone biosynthetic process
GO:0043524 IEA:EnsemblPnegative regulation of neuron apoptotic process
GO:0050885 IEA:EnsemblPneuromuscular process controlling balance
GO:0007274 IEA:EnsemblPneuromuscular synaptic transmission
GO:0042133 IEA:EnsemblPneurotransmitter metabolic process
GO:0007204 IDA:UniProtKBPpositive regulation of cytosolic calcium ion concentration
GO:0043113 IEA:EnsemblPreceptor clustering
GO:0014056 IEA:EnsemblPregulation of acetylcholine secretion, neurotransmission
GO:0050770 IEA:EnsemblPregulation of axonogenesis
GO:0017158 IEA:EnsemblPregulation of calcium ion-dependent exocytosis
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0060024 IEA:EnsemblPrhythmic synaptic transmission
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0021522 IEA:EnsemblPspinal cord motor neuron differentiation
GO:0000096 IEA:EnsemblPsulfur amino acid metabolic process
GO:0007416 IEA:EnsemblPsynapse assembly
GO:0007268 IBA:RefGenomePsynaptic transmission
GO:0035249 IEA:EnsemblPsynaptic transmission, glutamatergic
GO:0019226 IEA:EnsemblPtransmission of nerve impulse
GO:0021750 IEA:EnsemblPvestibular nucleus development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13606Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_13685Neuronal System
REACT_18325Regulation of insulin secretion
REACT_13477Transmission across Chemical Synapses
SMP Pathway Links
SMP IDDescription
SMP006793-Methylthiofentanyl Action Pathway
SMP00413Alfentanil Action Pathway
SMP00685Alvimopan Action Pathway
SMP00674Anileridine Action Pathway
SMP00392Benzocaine Action Pathway
SMP00393Bupivacaine Action Pathway
SMP00684Buprenorphine Action Pathway
SMP00414Carfentanil Action Pathway
SMP00394Chloroprocaine Action Pathway
SMP00424Citalopram Action Pathway
SMP00395Cocaine Action Pathway
SMP00405Codeine Action Pathway
SMP00423Desipramine Action Pathway
SMP00676Dezocine Action Pathway
SMP00396Dibucaine Action Pathway
SMP00689Dihydromorphine Action Pathway
SMP00680Dimethylthiambutene Action Pathway
SMP00675Diphenoxylate Action Pathway
SMP00425Escitalopram Action Pathway
SMP00681Ethylmorphine Action Pathway
SMP00415Fentanyl Action Pathway
SMP00426Fluoxetine Action Pathway
SMP00460Glibenclamide Action Pathway
SMP00461Gliclazide Action Pathway
SMP00407Heroin Action Pathway
SMP00411Hydrocodone Action Pathway
SMP00410Hydromorphone Action Pathway
SMP00422Imipramine Action Pathway
SMP00690Ketobemidone Action Pathway
SMP00683Levallorphan Action Pathway
SMP00397Levobupivacaine Action Pathway
SMP00677Levomethadyl Acetate Action Action Pathway
SMP00673Levorphanol Action Pathway
SMP00398Lidocaine (Local Anaesthetic) Action Pathway
SMP00399Mepivacaine Action Pathway
SMP00408Methadone Action Pathway
SMP00678Methadyl Acetate Action Pathway
SMP00406Morphine Action Pathway
SMP00691Nalbuphine Action Pathway
SMP00688Naloxone Action Pathway
SMP00687Naltrexone Action Pathway
SMP00453Nateglinide Action Pathway
SMP00431Nicotine Action Pathway
SMP00400Oxybuprocaine Action Pathway
SMP00409Oxycodone Action Pathway
SMP00412Oxymorphone Action Pathway
SMP00643Pancreas Function
SMP00686Pentazocine Action Pathway
SMP00401Prilocaine Action Pathway
SMP00402Procaine Action Pathway
SMP00403Proparacaine Action Pathway
SMP00672Propoxyphene Action Pathway
SMP00416Remifentanil Action Pathway
SMP00454Repaglinide Action Pathway
SMP00404Ropivacaine Action Pathway
SMP00417Sufentanil Action Pathway
SMP00671Tramadol Action Action Pathway
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