MGP Database

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MGP000396

Ontology/Pathway Information

Entrez Gene ID801
Gene Namecalmodulin 1 (phosphorylase kinase, delta)
Gene Symbol CALM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005813 IDA:UniProtKBCcentrosome
GO:0005737 TAS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005576 TAS:ReactomeCextracellular region
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0030426 IEA:EnsemblCgrowth cone
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 TAS:UniProtKBCplasma membrane
GO:0030017 IDA:BHF-UCLCsarcomere
GO:0005876 IDA:UniProtKBCspindle microtubule
GO:0000922 IDA:UniProtKBCspindle pole
GO:0031982 IDA:UniProtKBCvesicle
GO:0005509 IDA:BHF-UCLFcalcium ion binding
GO:0044325 IPI:BHF-UCLFion channel binding
GO:0030235 IEA:EnsemblFnitric-oxide synthase regulator activity
GO:0031997 IPI:UniProtKBFN-terminal myristoylation domain binding
GO:0043274 IPI:BHF-UCLFphospholipase binding
GO:0019904 IPI:UniProtKBFprotein domain specific binding
GO:0019901 IPI:BHF-UCLFprotein kinase binding
GO:0072542 IDA:BHF-UCLFprotein phosphatase activator activity
GO:0043539 TAS:BHF-UCLFprotein serine/threonine kinase activator activity
GO:0031996 IPI:UniProtKBFthioesterase binding
GO:0031432 IPI:BHF-UCLFtitin binding
GO:0007190 IEA:EnsemblPactivation of adenylate cyclase activity
GO:0007202 TAS:ReactomePactivation of phospholipase C activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0005513 IMP:BHF-UCLPdetection of calcium ion
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0006006 TAS:ReactomePglucose metabolic process
GO:0005980 TAS:ReactomePglycogen catabolic process
GO:0007186 TAS:UniProtKBPG-protein coupled receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0043647 TAS:ReactomePinositol phosphate metabolic process
GO:0061024 TAS:ReactomePmembrane organization
GO:0006936 TAS:ReactomePmuscle contraction
GO:0010801 TAS:BHF-UCLPnegative regulation of peptidyl-threonine phosphorylation
GO:0060315 ISS:BHF-UCLPnegative regulation of ryanodine-sensitive calcium-release channel activity
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0046209 TAS:ReactomePnitric oxide metabolic process
GO:0007603 TAS:ReactomePphototransduction, visible light
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0030801 IDA:BHF-UCLPpositive regulation of cyclic nucleotide metabolic process
GO:0051343 IDA:BHF-UCLPpositive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051000 IEA:EnsemblPpositive regulation of nitric-oxide synthase activity
GO:0010800 TAS:BHF-UCLPpositive regulation of peptidyl-threonine phosphorylation
GO:0032516 IDA:BHF-UCLPpositive regulation of phosphoprotein phosphatase activity
GO:0031954 TAS:BHF-UCLPpositive regulation of protein autophosphorylation
GO:0035307 IDA:BHF-UCLPpositive regulation of protein dephosphorylation
GO:0071902 TAS:BHF-UCLPpositive regulation of protein serine/threonine kinase activity
GO:0060316 IDA:BHF-UCLPpositive regulation of ryanodine-sensitive calcium-release channel activity
GO:0055117 IMP:BHF-UCLPregulation of cardiac muscle contraction
GO:0010881 IC:BHF-UCLPregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:1901844 IC:BHF-UCLPregulation of cell communication by electrical coupling involved in cardiac conduction
GO:0032465 IMP:UniProtKBPregulation of cytokinesis
GO:0002027 IMP:BHF-UCLPregulation of heart rate
GO:1901841 IEA:EnsemblPregulation of high voltage-gated calcium channel activity
GO:0050999 TAS:ReactomePregulation of nitric-oxide synthase activity
GO:0010880 IDA:BHF-UCLPregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0022400 TAS:ReactomePregulation of rhodopsin mediated signaling pathway
GO:0001975 IEA:EnsemblPresponse to amphetamine
GO:0051592 IDA:BHF-UCLPresponse to calcium ion
GO:0051412 IEA:EnsemblPresponse to corticosterone
GO:0016056 TAS:ReactomePrhodopsin mediated signaling pathway
GO:0007165 TAS:ReactomePsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0021762 IEP:UniProtKBPsubstantia nigra development
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_20652Activation of CaMK IV
REACT_21346Activation of Ca-permeable Kainate Receptor
REACT_21312Activation of Kainate Receptors upon glutamate binding
REACT_20563Activation of NMDA receptor upon glutamate binding and postsynaptic events
REACT_75774Adaptive Immune System
REACT_118700Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
REACT_264224beta-catenin independent WNT signaling
REACT_263982Ca2+ pathway
REACT_15307Ca-dependent events
REACT_9000Calmodulin induced events
REACT_15502CaMK IV-mediated phosphorylation of CREB
REACT_9053CaM pathway
REACT_15408Cam-PDE 1 activation
REACT_20642CREB phosphorylation through the activation of CaMKII
REACT_20661CREB phosphorylation through the activation of CaMKK
REACT_20568CREB phosphorylation through the activation of Ras
REACT_111064DAG and IP3 signaling
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_15334DARPP-32 events
REACT_116125Disease
REACT_160102Diseases associated with visual transduction
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_12478EGFR interacts with phospholipase C-gamma
REACT_12477eNOS activation
REACT_12389eNOS activation and regulation
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_163834FCERI mediated Ca+2 mobilization
REACT_723Glucose metabolism
REACT_1008Glycogen breakdown (glycogenolysis)
REACT_264090Glycogen storage diseases
REACT_15526G-protein mediated events
REACT_604Hemostasis
REACT_6900Immune System
REACT_163919Inactivation, recovery and regulation of the phototransduction cascade
REACT_6802Innate Immune System
REACT_150154Inositol phosphate metabolism
REACT_21322Ionotropic activity of Kainate Receptors
REACT_11123Membrane Trafficking
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_12508Metabolism of nitric oxide
REACT_264351Mitochondrial biogenesis
REACT_17044Muscle contraction
REACT_264430Myoclonic epilepsy of Lafora
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_15295Opioid Signalling
REACT_264135Organelle biogenesis and maintenance
REACT_21310Phospholipase C-mediated cascade
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_15426PLC beta mediated events
REACT_115720PLCG1 events in ERBB2 signaling
REACT_12079PLC-gamma1 signalling
REACT_20593Post NMDA receptor activation events
REACT_20546Ras activation uopn Ca2+ infux through NMDA receptor
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_115755Signaling by ERBB2
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_14797Signaling by GPCR
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888Signaling by PDGF
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_12529Signaling by VEGF
REACT_11045Signaling by Wnt
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_20558Smooth Muscle Contraction
REACT_150312Synthesis of IP3 and IP4 in the cytosol
REACT_111176Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
REACT_163722The phototransduction cascade
REACT_264212Transcriptional activation of mitochondrial biogenesis
REACT_147867Translocation of GLUT4 to the plasma membrane
REACT_13477Transmission across Chemical Synapses
REACT_264464VEGFA-VEGFR2 Pathway
REACT_264273VEGFR2 mediated cell proliferation
REACT_263991VEGFR2 mediated vascular permeability
REACT_160125Visual phototransduction
SMP Pathway Links
SMP IDDescription
SMP00296Acebutolol Action Pathway
SMP00297Alprenolol Action Pathway
SMP00665Amiodarone Action Pathway
SMP00376Amlodipine Action Pathway
SMP00664Arbutamine Action Pathway
SMP00298Atenolol Action Pathway
SMP00299Betaxolol Action Pathway
SMP00668Bevantolol Action Pathway
SMP00300Bisoprolol Action Pathway
SMP00657Bopindolol Action Pathway
SMP00670Bupranolol Action Pathway
SMP00658Carteolol Action Pathway
SMP00367Carvedilol Action Pathway
SMP00359Diltiazem Action Pathway
SMP00325Disopyramide Action Pathway
SMP00662Dobutamine Action Pathway
SMP00661Epinephrine Action Pathway
SMP00301Esmolol Action Pathway
SMP00377Felodipine Action Pathway
SMP00331Flecainide Action Pathway
SMP00326Fosphenytoin (Antiarrhythmic) Action Pathway
SMP00332Ibutilide Action Pathway
SMP00663Isoprenaline Action Pathway
SMP00378Isradipine Action Pathway
SMP00368Labetalol Action Pathway
SMP00666Levobunolol Action Pathway
SMP00328Lidocaine (Antiarrhythmic) Action Pathway
SMP00667Metipranolol Action Pathway
SMP00302Metoprolol Action Pathway
SMP00329Mexiletine Action Pathway
SMP00588Muscle/Heart Contraction
SMP00303Nadolol Action Pathway
SMP00366Nebivolol Action Pathway
SMP00379Nifedipine Action Pathway
SMP00380Nimodipine Action Pathway
SMP00381Nisoldipine Action Pathway
SMP00382Nitrendipine Action Pathway
SMP00304Oxprenolol Action Pathway
SMP00305Penbutolol Action Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00306Pindolol Action Pathway
SMP00669Practolol Action Pathway
SMP00324Procainamide (Antiarrhythmic) Action Pathway
SMP00307Propranolol Action Pathway
SMP00323Quinidine Action Pathway
SMP00660Sotalol Action Pathway
SMP00659Timolol Action Pathway
SMP00330Tocainide Action Pathway
SMP00375Verapamil Action Pathway
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