MGP Database

MGP000401

Ontology/Pathway Information

Entrez Gene ID814
Gene Namecalcium/calmodulin-dependent protein kinase IV
Gene Symbol CAMK4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005730 IDA:HPACnucleolus
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:HPACnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004683 IEA:UniProtKB-ECFcalmodulin-dependent protein kinase activity
GO:0007202 TAS:ReactomePactivation of phospholipase C activity
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0006954 IEA:UniProtKB-KWPinflammatory response
GO:0045087 TAS:ReactomePinnate immune response
GO:0007616 IGI:UniProtKBPlong-term memory
GO:0043011 IMP:UniProtKBPmyeloid dendritic cell differentiation
GO:0007270 IEA:EnsemblPneuron-neuron synaptic transmission
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0006913 IEA:EnsemblPnucleocytoplasmic transport
GO:0046827 IEA:EnsemblPpositive regulation of protein export from nucleus
GO:0045893 IDA:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0006468 TAS:ProtIncPprotein phosphorylation
GO:0045670 TAS:UniProtKBPregulation of osteoclast differentiation
GO:0033081 TAS:UniProtKBPregulation of T cell differentiation in thymus
GO:0007165 TAS:ReactomePsignal transduction
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_20652Activation of CaMK IV
REACT_20563Activation of NMDA receptor upon glutamate binding and postsynaptic events
REACT_15307Ca-dependent events
REACT_9000Calmodulin induced events
REACT_15502CaMK IV-mediated phosphorylation of CREB
REACT_9053CaM pathway
REACT_20661CREB phosphorylation through the activation of CaMKK
REACT_111064DAG and IP3 signaling
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_116125Disease
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_12478EGFR interacts with phospholipase C-gamma
REACT_15526G-protein mediated events
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_264351Mitochondrial biogenesis
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_15295Opioid Signalling
REACT_264135Organelle biogenesis and maintenance
REACT_21310Phospholipase C-mediated cascade
REACT_15426PLC beta mediated events
REACT_115720PLCG1 events in ERBB2 signaling
REACT_12079PLC-gamma1 signalling
REACT_20593Post NMDA receptor activation events
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_115755Signaling by ERBB2
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_14797Signaling by GPCR
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888Signaling by PDGF
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_264212Transcriptional activation of mitochondrial biogenesis
REACT_13477Transmission across Chemical Synapses
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