MGP Database

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MGP000429

Ontology/Pathway Information

Entrez Gene ID868
Gene NameCbl proto-oncogene B, E3 ubiquitin protein ligase
Gene Symbol CBLB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005634 IDA:HPACnucleus
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005509 IEA:InterProFcalcium ion binding
GO:0016874 IEA:UniProtKB-KWFligase activity
GO:0004871 IEA:InterProFsignal transducer activity
GO:0004842 IEA:InterProFubiquitin-protein transferase activity
GO:0008270 TAS:ProtIncFzinc ion binding
GO:0007166 IEA:InterProPcell surface receptor signaling pathway
GO:0006955 IEA:EnsemblPimmune response
GO:0035556 IEA:EnsemblPintracellular signal transduction
GO:0046642 IEA:EnsemblPnegative regulation of alpha-beta T cell proliferation
GO:0050860 IEA:EnsemblPnegative regulation of T cell receptor signaling pathway
GO:0006607 TAS:ProtIncPNLS-bearing protein import into nucleus
GO:0045732 IEA:EnsemblPpositive regulation of protein catabolic process
GO:0002669 IEA:EnsemblPpositive regulation of T cell anergy
GO:0007165 TAS:ProtIncPsignal transduction
GO:0042110 IEA:EnsemblPT cell activation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_118700Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
REACT_75842Antigen processing: Ubiquitination & Proteasome degradation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_6900Immune System
REACT_118773Signaling by the B Cell Receptor (BCR)
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