MGP Database

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MGP000433

Ontology/Pathway Information

Entrez Gene ID875
Gene Namecystathionine-beta-synthase
Gene Symbol CBS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:UniProtKBCcytosol
GO:0005634 IDA:UniProtKBCnucleus
GO:0030554 IEA:InterProFadenyl nucleotide binding
GO:0004122 IDA:UniProtKBFcystathionine beta-synthase activity
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0020037 IDA:UniProtKBFheme binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0072341 IDA:UniProtKBFmodified amino acid binding
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0030170 IDA:UniProtKBFpyridoxal phosphate binding
GO:0031625 IPI:UniProtKBFubiquitin protein ligase binding
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0006535 IEA:InterProPcysteine biosynthetic process from serine
GO:0019343 IEA:InterProPcysteine biosynthetic process via cystathionine
GO:0043418 IDA:UniProtKBPhomocysteine catabolic process
GO:0050667 IDA:UniProtKBPhomocysteine metabolic process
GO:0070814 IDA:UniProtKBPhydrogen sulfide biosynthetic process
GO:0019448 IDA:UniProtKBPL-cysteine catabolic process
GO:0006565 IDA:UniProtKBPL-serine catabolic process
GO:0006563 IDA:UniProtKBPL-serine metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0000096 TAS:ReactomePsulfur amino acid metabolic process
GO:0019346 TAS:ReactomePtranssulfuration
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115589Cysteine formation from homocysteine
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_115639Sulfur amino acid metabolism
SMP Pathway Links
SMP IDDescription
SMP007213-Phosphoglycerate dehydrogenase deficiency
SMP00177Cystathionine Beta-Synthase Deficiency
SMP00179Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
SMP00242Dimethylglycine Dehydrogenase Deficiency
SMP00484Dimethylglycinuria
SMP00514Gamma-cystathionase deficiency (CTH)
SMP00004Glycine and Serine Metabolism
SMP00222Glycine N-methyltransferase Deficiency
SMP00455Homocysteine Degradation
SMP00515Homocystinuria, cystathionine beta-synthase deficiency
SMP00570Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblG complementation type
SMP00485Hyperglycinemia, non-ketotic
SMP00341Hypermethioninemia
SMP00221Methionine Adenosyltransferase Deficiency
SMP00033Methionine Metabolism
SMP00340Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)
SMP00223Non Ketotic Hyperglycinemia
SMP00214S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
SMP00244Sarcosinemia
SMP00029Selenoamino Acid Metabolism
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