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MGP000435

UniProt Annotations

Entry Information
Gene Namecholecystokinin
Protein EntryCCKN_HUMAN
UniProt IDP06307
SpeciesHuman
Comments
Comment typeDescription
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
PtmThe precursor is cleaved by proteases to produce a number of active cholecystokinins.
SimilarityBelongs to the gastrin/cholecystokinin family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitBinds to CCK-A receptors in the pancreas and CCK-B receptors in the brain. {ECO:0000250}.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cck/";
Web ResourceName=Wikipedia; Note=Cholecystokinin entry; URL="http://en.wikipedia.org/wiki/Cholecystokinin";
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