MGP Database

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MGP000461

Record overview

MGPD IDMGP000461
Gene ID948
SpeciesHomo sapiens (Human)
Gene NameCD36 molecule (thrombospondin receptor)
Gene Symbol CD36
SynonymsFAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10;
Alternate namesplatelet glycoprotein 4; CD36 antigen (collagen type I receptor, thrombospondin receptor); GPIIIB; PAS IV; PAS-4 protein; cluster determinant 36; fatty acid translocase; glycoprotein IIIb; leukocyte differentiation antigen CD36; platelet glycoprotein IV; scavenger receptor class B, member 3;
Chromosome7
Map Location7q11.2
SummaryThe protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
OrthologsView orthologs and multiple alignments for CD36

Proteins

platelet glycoprotein 4 isoform 1
Refseq ID:NP_001120915
Protein GI:188536063
UniProt ID:P16671
mRNA ID:NM_001127443
Length:472
RefSeq Status:
MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAK
ENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLWGYRDPFLSLVPYPVTTTVGL
FYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAF
ASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQ
VLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFMISYCACRSKTIK
 
platelet glycoprotein 4 isoform 1
Refseq ID:NP_000063
Protein GI:48375178
UniProt ID:P16671
mRNA ID:NM_000072
Length:472
RefSeq Status:
Protein sequence is identical to GI:188536063 (mRNA isoform)
 
platelet glycoprotein 4 isoform 1
Refseq ID:NP_001001547
Protein GI:48375176
UniProt ID:P16671
mRNA ID:NM_001001547
Length:472
RefSeq Status:
Protein sequence is identical to GI:188536063 (mRNA isoform)
 
platelet glycoprotein 4 isoform 1
Refseq ID:NP_001120916
Protein GI:188536065
UniProt ID:P16671
mRNA ID:NM_001127444
Length:472
RefSeq Status:
Protein sequence is identical to GI:188536063 (mRNA isoform)
 
platelet glycoprotein 4 isoform 1
Refseq ID:NP_001001548
Protein GI:48375180
UniProt ID:P16671
mRNA ID:NM_001001548
Length:472
RefSeq Status:
Protein sequence is identical to GI:188536063 (mRNA isoform)
 
platelet glycoprotein 4 isoform 2
Refseq ID:NP_001276837
Protein GI:583966140
UniProt ID:P16671
mRNA ID:NM_001289908
Length:433
RefSeq Status:
MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAK
ENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLWGYRDPFLSLVPYPVTTTVGL
FYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPV
YISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKIN
LLGLIEMILLSVGVVMFVAFMISYCACRSKTIK
 
platelet glycoprotein 4 isoform 3
Refseq ID:NP_001276838
Protein GI:583966144
UniProt ID:P16671
mRNA ID:NM_001289909
Length:412
RefSeq Status:
MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAK
ENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEK
SQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGL
NPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFM
ISYCACRSKTIK
 
platelet glycoprotein 4 isoform 4
Refseq ID:NP_001276840
Protein GI:583966150
UniProt ID:P16671
mRNA ID:NM_001289911
Length:396
RefSeq Status:
MMNSSNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLR
ELLWGYRDPFLSLVPYPVTTTVGLFYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIY
AVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPI
TGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFMISYCACRSKTIK
 
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