MGP Database

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MGP000464

Ontology/Pathway Information

Entrez Gene ID960
Gene NameCD44 molecule (Indian blood group)
Gene Symbol CD44
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016323 IEA:EnsemblCbasolateral plasma membrane
GO:0009986 IDA:UniProtKBCcell surface
GO:0005737 IDA:HPACcytoplasm
GO:0009897 IEA:EnsemblCexternal side of plasma membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005794 IDA:HPACGolgi apparatus
GO:0005887 NAS:UniProtKBCintegral component of plasma membrane
GO:0035692 IDA:BHF-UCLCmacrophage migration inhibitory factor receptor complex
GO:0005886 IDA:HPACplasma membrane
GO:0005518 NAS:UniProtKBFcollagen binding
GO:0005540 IDA:UniProtKBFhyaluronic acid binding
GO:0004415 IDA:UniProtKBFhyalurononglucosaminidase activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0060442 IEA:EnsemblPbranching involved in prostate gland morphogenesis
GO:0001658 IEA:EnsemblPbranching involved in ureteric bud morphogenesis
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0051216 IEP:UniProtKBPcartilage development
GO:0007160 NAS:UniProtKBPcell-matrix adhesion
GO:0044344 IDA:UniProtKBPcellular response to fibroblast growth factor stimulus
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0030203 TAS:ReactomePglycosaminoglycan metabolic process
GO:0030214 IDA:UniProtKBPhyaluronan catabolic process
GO:0030212 TAS:ReactomePhyaluronan metabolic process
GO:0060333 TAS:ReactomePinterferon-gamma-mediated signaling pathway
GO:0050900 TAS:ReactomePleukocyte migration
GO:0070487 IMP:UniProtKBPmonocyte aggregation
GO:0043066 IMP:UniProtKBPnegative regulation of apoptotic process
GO:0043154 IMP:UniProtKBPnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043518 IDA:BHF-UCLPnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:1902166 IDA:BHF-UCLPnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070374 IDA:BHF-UCLPpositive regulation of ERK1 and ERK2 cascade
GO:0010628 IEA:EnsemblPpositive regulation of gene expression
GO:0034116 IMP:UniProtKBPpositive regulation of heterotypic cell-cell adhesion
GO:1900625 IMP:BHF-UCLPpositive regulation of monocyte aggregation
GO:0033138 IDA:BHF-UCLPpositive regulation of peptidyl-serine phosphorylation
GO:0050731 IDA:BHF-UCLPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0016337 NAS:UniProtKBPsingle organismal cell-cell adhesion
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0016055 IEA:EnsemblPWnt signaling pathway
GO:0002246 IEA:EnsemblPwound healing involved in inflammatory response
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_12051Cell surface interactions at the vascular wall
REACT_75790Cytokine Signaling in Immune system
REACT_268678Defective B3GAT3 causes JDSSDHD
REACT_268431Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
REACT_268749Defective B4GALT7 causes EDS, progeroid type
REACT_267917Defective CHST14 causes EDS, musculocontractural type
REACT_267648Defective CHST3 causes SEDCJD
REACT_268786Defective CHST6 causes MCDC1
REACT_268113Defective CHSY1 causes TPBS
REACT_267942Defective EXT1 causes exostoses 1, TRPS2 and CHDS
REACT_267741Defective EXT2 causes exostoses 2
REACT_268843Defective PAPSS2 causes SEMD-PA
REACT_268059Defective SLC26A2 causes chondrodysplasias
REACT_118572Degradation of the extracellular matrix
REACT_116125Disease
REACT_268624Diseases associated with glycosaminoglycan metabolism
REACT_268324Diseases of glycosylation
REACT_118779Extracellular matrix organization
REACT_264090Glycogen storage diseases
REACT_121315Glycosaminoglycan metabolism
REACT_604Hemostasis
REACT_121083Hyaluronan metabolism
REACT_120996Hyaluronan uptake and degradation
REACT_6900Immune System
REACT_13552Integrin cell surface interactions
REACT_25078Interferon gamma signaling
REACT_25229Interferon Signaling
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_147857MPS I - Hurler syndrome
REACT_147734MPS II - Hunter syndrome
REACT_147753MPS IIIA - Sanfilippo syndrome A
REACT_147788MPS IIIB - Sanfilippo syndrome B
REACT_147860MPS IIIC - Sanfilippo syndrome C
REACT_147749MPS IIID - Sanfilippo syndrome D
REACT_147825MPS IV - Morquio syndrome A
REACT_147798MPS IV - Morquio syndrome B
REACT_147739MPS IX - Natowicz syndrome
REACT_147759MPS VII - Sly syndrome
REACT_147719MPS VI - Maroteaux-Lamy syndrome
REACT_147853Mucopolysaccharidoses
REACT_264430Myoclonic epilepsy of Lafora
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