MGP Database

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MGP000472

Record overview

MGPD IDMGP000472
Gene ID973
SpeciesHomo sapiens (Human)
Gene NameCD79a molecule, immunoglobulin-associated alpha
Gene Symbol CD79A
SynonymsIGA; MB-1;
Alternate namesB-cell antigen receptor complex-associated protein alpha chain; ig-alpha; MB-1 membrane glycoprotein; surface IgM-associated protein; CD79a antigen (immunoglobulin-associated alpha); membrane-bound immunoglobulin-associated protein;
Chromosome19
Map Location19q13.2
SummaryThe B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CD79A

Proteins

B-cell antigen receptor complex-associated protein alpha chain isoform 1 precursor
Refseq ID:NP_001774
Protein GI:4502685
UniProt ID:P11912
mRNA ID:NM_001783
Length:226
RefSeq Status:
MPGGPGVLQALPATIFLLFLLSAVYLGPGCQALWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNGTLIIQNVNKSH
GGIYVCRVQEGNESYQQSCGTYLRVRQPPPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKLGLDAGDEYEDENLYEGLNLDDCSMYE
DISRGLQGTYQDVGSLNIGDVQLEKP
 
sig_peptide: 1..32
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3216
peptide sequence: 
MPGGPGVLQALPATIFLLFLLSAVYLGPGCQA

mat_peptide: 33..188
product: B-cell antigen receptor complex-associated protein alpha chain isoform 2
calculated_mol_wt: 17588
peptide sequence: 
LWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNEPPPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQ
NEKLGLDAGDEYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGSLNIGDVQLEKP

sig_peptide: 1..32
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3216
peptide sequence: 
MPGGPGVLQALPATIFLLFLLSAVYLGPGCQA

mat_peptide: 33..226
product: B-cell antigen receptor complex-associated protein alpha chain isoform 1
calculated_mol_wt: 21841
peptide sequence: 
LWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNGTLIIQNVNKSHGGIYVCRVQEGNESYQQSCGTYLRVRQPPPRP
FLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKLGLDAGDEYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGSLNIGDVQLEKP
 
B-cell antigen receptor complex-associated protein alpha chain isoform 2 precursor
Refseq ID:NP_067612
Protein GI:11038672
UniProt ID:P11912
mRNA ID:NM_021601
Length:188
RefSeq Status:
MPGGPGVLQALPATIFLLFLLSAVYLGPGCQALWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNEPPPRPFLDMGE
GTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKLGLDAGDEYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGSLNIGDVQLEKP
 
sig_peptide: 1..32
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3216
peptide sequence: 
MPGGPGVLQALPATIFLLFLLSAVYLGPGCQA

mat_peptide: 33..188
product: B-cell antigen receptor complex-associated protein alpha chain isoform 2
calculated_mol_wt: 17588
peptide sequence: 
LWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNEPPPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQ
NEKLGLDAGDEYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGSLNIGDVQLEKP
 
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