MGP Database

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MGP000483

Ontology/Pathway Information

Entrez Gene ID993
Gene Namecell division cycle 25A
Gene Symbol CDC25A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0004725 IEA:UniProtKB-ECFprotein tyrosine phosphatase activity
GO:0008283 TAS:UniProtKBPcell proliferation
GO:0034644 IDA:UniProtKBPcellular response to UV
GO:0006260 TAS:ReactomePDNA replication
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007067 IEA:UniProtKB-KWPmitotic nuclear division
GO:0051726 TAS:ReactomePregulation of cell cycle
GO:0000079 TAS:UniProtKBPregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0009314 IDA:UniProtKBPresponse to radiation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6769Activation of ATR in response to replication stress
REACT_115566Cell Cycle
REACT_1538Cell Cycle Checkpoints
REACT_152Cell Cycle, Mitotic
REACT_1857Cyclin A/B1 associated events during G2/M transition
REACT_9029Cyclin A:Cdk2-associated events at S phase entry
REACT_2101Cyclin B2 mediated events
REACT_1574Cyclin E associated events during G1/S transition
REACT_1321E2F-enabled inhibition of pre-replication complex formation
REACT_471E2F mediated regulation of DNA replication
REACT_111214G0 and Early G1
REACT_2254G1/S DNA Damage Checkpoints
REACT_683G1/S-Specific Transcription
REACT_1783G1/S Transition
REACT_828G2/M Checkpoints
REACT_2203G2/M Transition
REACT_21267Mitotic G1-G1/S phases
REACT_21391Mitotic G2-G2/M phases
REACT_2160p53-Independent DNA Damage Response
REACT_1208p53-Independent G1/S DNA damage checkpoint
REACT_1006Polo-like kinase mediated events
REACT_899S Phase
REACT_1614Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
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