MGP Database

MGP000490

Ontology/Pathway Information

Entrez Gene ID	1000
Gene Name	cadherin 2, type 1, N-cadherin (neuronal)
Gene Symbol	CDH2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016324	IEA:Ensembl	C	apical plasma membrane
GO:0016342	IDA:BHF-UCL	C	catenin complex
GO:0005913	IDA:BHF-UCL	C	cell-cell adherens junction
GO:0005911	IDA:BHF-UCL	C	cell-cell junction
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005916	IEA:Ensembl	C	fascia adherens
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0014704	ISS:BHF-UCL	C	intercalated disc
GO:0030027	IEA:Ensembl	C	lamellipodium
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0045202	IEA:Ensembl	C	synapse
GO:0045294	IPI:BHF-UCL	F	alpha-catenin binding
GO:0008013	TAS:AgBase	F	beta-catenin binding
GO:0005509	IEA:InterPro	F	calcium ion binding
GO:0045295	IPI:BHF-UCL	F	gamma-catenin binding
GO:0034332	TAS:Reactome	P	adherens junction organization
GO:0048514	IEA:Ensembl	P	blood vessel morphogenesis
GO:0016339	IEA:Ensembl	P	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007155	TAS:ProtInc	P	cell adhesion
GO:0044331	ISS:UniProtKB	P	cell-cell adhesion mediated by cadherin
GO:0045216	TAS:Reactome	P	cell-cell junction organization
GO:0034329	TAS:Reactome	P	cell junction assembly
GO:0016477	IEA:Ensembl	P	cell migration
GO:0010001	ISS:UniProtKB	P	glial cell differentiation
GO:0007157	IEA:Ensembl	P	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007156	IEA:Ensembl	P	homophilic cell adhesion via plasma membrane adhesion molecules
GO:0042692	TAS:Reactome	P	muscle cell differentiation
GO:0090090	IEA:Ensembl	P	negative regulation of canonical Wnt signaling pathway
GO:0097150	ISS:UniProtKB	P	neuronal stem cell maintenance
GO:0043410	IEA:Ensembl	P	positive regulation of MAPK cascade
GO:0051149	TAS:Reactome	P	positive regulation of muscle cell differentiation
GO:0051146	IEA:Ensembl	P	striated muscle cell differentiation

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_19195	Adherens junctions interactions
REACT_21402	CDO in myogenesis
REACT_111155	Cell-Cell communication
REACT_19331	Cell-cell junction organization
REACT_20676	Cell junction organization
REACT_111045	Developmental Biology
REACT_21303	Myogenesis