MGP Database

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MGP000550

Ontology/Pathway Information

Entrez Gene ID1131
Gene Namecholinergic receptor, muscarinic 3
Gene Symbol CHRM3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0032279 IEA:EnsemblCasymmetric synapse
GO:0043679 IEA:EnsemblCaxon terminus
GO:0016323 IEA:UniProtKB-SubCellCbasolateral plasma membrane
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0030425 IEA:EnsemblCdendrite
GO:0005887 ISS:UniProtKBCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0045211 IEA:UniProtKB-SubCellCpostsynaptic membrane
GO:0042166 ISS:UniProtKBFacetylcholine binding
GO:0008144 IEA:EnsemblFdrug binding
GO:0016907 ISS:UniProtKBFG-protein coupled acetylcholine receptor activity
GO:0004435 TAS:ProtIncFphosphatidylinositol phospholipase C activity
GO:0004872 TAS:ProtIncFreceptor activity
GO:0008283 TAS:ProtIncPcell proliferation
GO:0006464 TAS:ProtIncPcellular protein modification process
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0007213 ISS:UniProtKBPG-protein coupled acetylcholine receptor signaling pathway
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0007399 TAS:ProtIncPnervous system development
GO:0045987 IEA:EnsemblPpositive regulation of smooth muscle contraction
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0003056 IEA:EnsemblPregulation of vascular smooth muscle contraction
GO:0046541 IEA:InterProPsaliva secretion
GO:0007165 TAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006939 IEA:EnsemblPsmooth muscle contraction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18405Acetylcholine regulates insulin secretion
REACT_16983Amine ligand-binding receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_1505Integration of energy metabolism
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_16943Muscarinic acetylcholine receptors
REACT_18325Regulation of insulin secretion
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00736Betazole Action Pathway
SMP00232Cimetidine Action Pathway
SMP00225Esomeprazole Action Pathway
SMP00231Famotidine Action Pathway
SMP00589Gastric Acid Production
SMP00227Lansoprazole Action Pathway
SMP00735Metiamide Action Pathway
SMP00233Nizatidine Action Pathway
SMP00226Omeprazole Action Pathway
SMP00228Pantoprazole Action Pathway
SMP00246Pirenzepine Action Pathway
SMP00229Rabeprazole Action Pathway
SMP00230Ranitidine Action Pathway
SMP00734Roxatidine acetate Action Pathway
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