MGP Database

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MGP000555

Ontology/Pathway Information

Entrez Gene ID1136
Gene Namecholinergic receptor, nicotinic, alpha 3 (neuronal)
Gene Symbol CHRNA3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005892 IDA:UniProtKBCacetylcholine-gated channel complex
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0030425 ISS:UniProtKBCdendrite
GO:0016021 NAS:UniProtKBCintegral component of membrane
GO:0043025 ISS:UniProtKBCneuronal cell body
GO:0005886 TAS:ReactomeCplasma membrane
GO:0014069 ISS:UniProtKBCpostsynaptic density
GO:0045211 IEA:UniProtKB-SubCellCpostsynaptic membrane
GO:0004889 IDA:UniProtKBFacetylcholine-activated cation-selective channel activity
GO:0042166 IC:UniProtKBFacetylcholine binding
GO:0015464 IDA:UniProtKBFacetylcholine receptor activity
GO:0015276 TAS:DFLATFligand-gated ion channel activity
GO:0007171 ISS:UniProtKBPactivation of transmembrane receptor protein tyrosine kinase activity
GO:0035095 IMP:UniProtKBPbehavioral response to nicotine
GO:0098655 IDA:GOCPcation transmembrane transport
GO:0006812 IDA:GOCPcation transport
GO:0034220 TAS:GOCPion transmembrane transport
GO:0006811 NAS:UniProtKBPion transport
GO:0007626 ISS:UniProtKBPlocomotory behavior
GO:0007399 IMP:UniProtKBPnervous system development
GO:0014056 ISS:UniProtKBPregulation of acetylcholine secretion, neurotransmission
GO:0048814 ISS:UniProtKBPregulation of dendrite morphogenesis
GO:0060079 ISS:UniProtKBPregulation of excitatory postsynaptic membrane potential
GO:0042391 ISS:UniProtKBPregulation of membrane potential
GO:0006940 ISS:UniProtKBPregulation of smooth muscle contraction
GO:0007165 IDA:UniProtKBPsignal transduction
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0007271 ISS:UniProtKBPsynaptic transmission, cholinergic
GO:0060084 IMP:UniProtKBPsynaptic transmission involved in micturition
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15461Acetylcholine Binding And Downstream Events
REACT_22126Activation of Nicotinic Acetylcholine Receptors
REACT_22352Highly calcium permeable nicotinic acetylcholine receptors
REACT_22303Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
REACT_22223Highly sodium permeable acetylcholine nicotinic receptors
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_22149Postsynaptic nicotinic acetylcholine receptors
REACT_22336Presynaptic nicotinic acetylcholine receptors
REACT_13477Transmission across Chemical Synapses
SMP Pathway Links
SMP IDDescription
SMP00431Nicotine Action Pathway
SMP00628Nicotine Metabolism Pathway
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