MGP Database

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MGP000574

Ontology/Pathway Information

Entrez Gene ID1173
Gene Nameadaptor-related protein complex 2, mu 1 subunit
Gene Symbol AP2M1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030122 TAS:BHF-UCLCAP-2 adaptor complex
GO:0030669 TAS:ReactomeCclathrin-coated endocytic vesicle membrane
GO:0005829 TAS:ReactomeCcytosol
GO:0030666 TAS:ReactomeCendocytic vesicle membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005765 TAS:ReactomeClysosomal membrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005886 TAS:ReactomeCplasma membrane
GO:0008289 IEA:UniProtKB-KWFlipid binding
GO:0050750 ISS:BHF-UCLFlow-density lipoprotein particle receptor binding
GO:0005048 IDA:BHF-UCLFsignal sequence binding
GO:0005215 TAS:ProtIncFtransporter activity
GO:0019886 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0007411 TAS:ReactomePaxon guidance
GO:0072583 TAS:BHF-UCLPclathrin-mediated endocytosis
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0006886 IEA:InterProPintracellular protein transport
GO:0061024 TAS:ReactomePmembrane organization
GO:0042059 TAS:ReactomePnegative regulation of epidermal growth factor receptor signaling pathway
GO:1903077 IMP:UniProtKBPnegative regulation of protein localization to plasma membrane
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0050690 TAS:ReactomePregulation of defense response to virus by virus
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_18266Axon guidance
REACT_264224beta-catenin independent WNT signaling
REACT_111045Developmental Biology
REACT_116125Disease
REACT_12484EGFR downregulation
REACT_264198EPH-ephrin mediated repulsion of cells
REACT_264068EPH-Ephrin signaling
REACT_11049Formation of annular gap junctions
REACT_11035Gap junction degradation
REACT_9411Gap junction trafficking
REACT_9480Gap junction trafficking and regulation
REACT_6185HIV Infection
REACT_6288Host Interactions of HIV factors
REACT_6900Immune System
REACT_22205L1CAM interactions
REACT_11123Membrane Trafficking
REACT_121399MHC class II antigen presentation
REACT_11166Nef Mediated CD4 Down-regulation
REACT_11200Nef Mediated CD8 Down-regulation
REACT_11139Nef mediated downregulation of CD28 cell surface expression
REACT_11149Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_264199PCP/CE pathway
REACT_22365Recycling pathway of L1
REACT_12435Retrograde neurotrophin signalling
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_11045Signaling by Wnt
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_6835The role of Nef in HIV-1 replication and disease pathogenesis
REACT_263890WNT5A-dependent internalization of FZD4
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