MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000589

Record overview

MGPD IDMGP000589
Gene ID1193
SpeciesHomo sapiens (Human)
Gene Namechloride intracellular channel 2
Gene Symbol CLIC2
SynonymsCLIC2b; MRXS32; XAP121;
Alternate nameschloride intracellular channel protein 2;
ChromosomeX
Map LocationXq28
SummaryThis gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein may play a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of X-linked mental retardation-32. [provided by RefSeq, Aug 2013]
OrthologsView orthologs and multiple alignments for CLIC2

Proteins

chloride intracellular channel protein 2
Refseq ID:NP_001280
Protein GI:66346733
UniProt ID:O15247
mRNA ID:NM_001289
Length:247
RefSeq Status:
MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYP
HLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKY
RDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQKS
 
  logo