MGP Database

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MGP000590

Ontology/Pathway Information

Entrez Gene ID1200
Gene Nametripeptidyl peptidase I
Gene Symbol TPP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0043202 TAS:ReactomeClysosomal lumen
GO:0005764 IDA:UniProtKBClysosome
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0005739 IEA:EnsemblCmitochondrion
GO:0004175 IDA:UniProtKBFendopeptidase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0008233 IMP:UniProtKBFpeptidase activity
GO:0042277 ISS:UniProtKBFpeptide binding
GO:0004252 IEA:InterProFserine-type endopeptidase activity
GO:0008236 IMP:UniProtKBFserine-type peptidase activity
GO:0008240 IDA:UniProtKBFtripeptidyl-peptidase activity
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0045453 IMP:UniProtKBPbone resorption
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0030855 IEP:UniProtKBPepithelial cell differentiation
GO:0006629 TAS:ProtIncPlipid metabolic process
GO:0007040 ISS:UniProtKBPlysosome organization
GO:0007399 IMP:UniProtKBPnervous system development
GO:0050885 ISS:UniProtKBPneuromuscular process controlling balance
GO:0043171 IMP:UniProtKBPpeptide catabolic process
GO:0030163 NAS:UniProtKBPprotein catabolic process
GO:0006508 IMP:UniProtKBPproteolysis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18368IRE1alpha activates chaperones
REACT_17015Metabolism of proteins
REACT_18356Unfolded Protein Response (UPR)
REACT_18273XBP1(S) activates chaperone genes
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